老年2型糖尿病合并非酒精性脂肪肝与下肢动脉疾病的关系  

The relationship between lower extremity atherosclerotic disease and non-alcoholic fatty liver in aged patients with type 2 diabetes mellitus

作　　者：王曼曼[1] 曾龙驿[1] 孙艳[1] 舒冏[1] 张国超[1] 穆攀伟[1] 陈燕铭[1] 

机构地区：[1]中山大学附属第三医院内分泌科,510630

出　　处：《中国临床实用医学》2009年第12期98-99,共2页China Clinical Practical Medicine

摘　　要：目的探讨老年2型糖尿病（T2DM）合并非酒精性脂肪肝的发生与下肢动脉疾病（LEAD）的关系。方法对89例老年2型糖尿病患者，根据有无合并非酒精性脂肪肝分为合并脂肪肝组和非脂肪肝组。对这些患者进行体格检查、生化检查及下肢动脉彩色多普勒超声检查。结果老年2型糖尿病合并脂肪肝组BMI、WHR、FINS、HOMA—IR、LDL—C、TG较非脂肪肝组升高（P〈0．05）。两组间LEAD发生率无显著性差异，但合并脂肪肝组重度及极重度LEAD发生率较高。结论老年2型糖尿病合并脂肪肝组更易出现血脂异常、胰岛素抵抗及较严重下肢动脉疾病。Objective To investigate the relationship between lower extremity atherosclerotic disease （LEAD） and non-alcoholic fatty liver （NAFL） in aged patients with type 2 diabetes mellitus （T2DM） . Methods According to whether the patients had NAFL, 89 cases of aged patients with T2DM were divided into fatty liver group and non-fatty liver group. The physical examination, biochemical tests and ultrasonic Doppler examinations were conducted in these patients. Results The levels of BMI, WHR, FINS, HOMA-IR, LDL-C and TG increased significandy in fatty liver group compared with non-fatty liver group （ P 〈 0. 05 ）. The incidence of LEAD was not different between two groups , but the incidence of more severe LEAD was higher in the group with NAFL. Conclusion NAFL in aged T2DM patients have remarkable dyslipidemia, insulin resistance and severe LEAD.

关 键 词：2型糖尿病 脂肪肝 下肢动脉疾病 

分 类 号：R575[医药卫生—消化系统] R587[医药卫生—内科学]