CT脑灌注成像在短暂性脑缺血发作中的应用  

Application of CT perfusion imaging in the diagnosis of TIA

作　　者：康孝理[1] 许俊萍[2] 姜丙全[2] 赵玉铁[2] 刘四化[2] 

机构地区：[1]河南濮阳市油田总医院神经内科,濮阳457001 [2]河南濮阳市油田总医院急诊科,濮阳457001

出　　处：《中国实用神经疾病杂志》2009年第24期28-30,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨CT灌注成像（CTP）对短暂性脑缺血发作（TIA）的诊断价值及相关病因的检查方法。方法35例TIA患者均在发病24h内行CT和CTP检查，在发病12～72h行头颅MRI及MRA检查，分别就CT检出的病灶和MRI检出的病灶与CTP检查的结果相比较。结果CT共检出21个病灶，头颅MRI共检出26个病灶，CTP共检出38个病灶，其中11个病灶表现为相对血流量（RF）降低，CT脑灌注的最大峰值时间（PT）与平均通过时间（MTT）延长。6个病灶RF与对比区域相比无明显降低，其MTT略延长，PT时间明显延长。结论CTP对TIA的诊断具有超早性和定位价值。从而能及时追查病因，避免大面积脑梗死的发生，可做为TIA的常规检查项目。Objective To explore the diagnosis value of CT perfusion imaging on TIA. Methods In 35 TIA patients, CT and CTP were performed in 24 hours after TIA onset, MRI and MRA were performed in 12-72h. The detection efficiencies of these imaging methods were evaluated. Results Twenty-one, twenty-six and thirty-eight ischemic lesions were detected by CT, MRI and CTP, respectively. Eleyen lesions detected by CTP showed relatively decreased blood flow and prolonged peak time （PT） and mean transit time （MTT）; Six lesions showed significantly prolonged MTT and slightly prolonged PT, but no change in blood flow. Conclusion CTP might be a valuable tool in detecting ischemie lesions of TIA. It could be routinely applied in lhe early diagnosis of TIA.

关 键 词：体层摄影术 X线计算机 短暂性脑缺血 脑灌注 局部血流 

分 类 号：R743.31[医药卫生—神经病学与精神病学]