过度摄入黄酮的潜在危害  

Potential Health Impacts of Exorbitant Flavonoid Intake

作　　者：路燕[1] 李军生[1] 阎柳娟[1] 

机构地区：[1]广西工学院,广西柳州545006

出　　处：《时珍国医国药》2009年第12期3079-3081,共3页Lishizhen Medicine and Materia Medica Research

基　　金：广西科学研究与技术开发计划应用基础研究专项项目(No.0575023)

摘　　要：近来,黄酮类被作为抗癌、抗氧化等多功效物质,日益升温。然而,人们往往忽略了过多的摄食黄酮类物质的潜在危险。尽管黄酮表现出有益健康的效果,但一些研究指出了它们的诱变性和遗传毒性。文章通过DNA嵌入剂原理来解释过度摄入黄酮类物质的潜在危害。Recently, a renewed interest in flavonoids has been fueled by the functional effects ascribed to anticarcinogens and antioxidant and so on. Unfortunately, the potentially toxic effects of excessive flavonoid intake are largely ignored. Despite the apparent beneficial health effects of flavonoids, several studies indicate their mutagenicity and genotoxicity in both bacterial and mammalian experimental systems. This essay explained the potential health impacts of flavonoid intake through DNA intercalators principle.

关 键 词：黄酮类物质 诱变性 基因毒性 DNA嵌入剂 

分 类 号：Q-1[生物学] X912[环境科学与工程—安全科学]