插植调强近距离放射治疗复发性宫颈癌的临床研究  

Inplanted intensity modulated brachytherapy for the recurred cervical carcinoma

作　　者：叶伟军[1] 曹新平[1] 李爱菊[1] 任玉峰[1] 陈凯[1] 张志斌[2] 

机构地区：[1]华南肿瘤学国家重点实验室中山大学肿瘤防治中心放射治疗科,广东广州510060 [2]华南肿瘤学国家重点实验室中山大学肿瘤防治中心物业管理科,广东广州510060

出　　处：《中华肿瘤防治杂志》2009年第18期1427-1429,共3页Chinese Journal of Cancer Prevention and Treatment

摘　　要：为了探讨盆腔插植调强近距离放射治疗在复发性宫颈癌中的价值,选择25例盆腔复发性宫颈癌患者行插植后装调强近距离放疗为实验组,同期行常规后装放疗的25例盆腔复发性宫颈癌患者作为对照组,比较两组间的近期疗效及并发症。实验组CR20例,PR5例;对照组CR10例,PR7例,SD4例,PD4例,两组比较差异有统计学意义,P<0.005。实验组出现5例阴道直肠瘘,1例3级肠炎;对照组出现4例阴道直肠瘘,1例3级肠炎,两组比较差异无统计学意义,P>0.005。初步研究结果提示,盆腔插植调强近距离放射治疗复发性宫颈癌近期疗效满意,优于常规近距离放疗,毒副反应可耐受。The objective of this study was to explore the value of pelvic inplanted intensity modulated brachytherapy for the recurred cervical carcinoma. A total of 50 patients of recurred cervical carcinoma were enrolled into the trial group（25 cases） which were treated by pelvic inplanted afterloading intensity modulated brachytherapy and the comparison group（25 cases） which were treated by the routine brachytherapy. There were 20 cases CR and 5 cases PR in the trial group,and 10 cases CR,7 cases PR,4 cases SD and 4 cases PD in the comparison group. The difference between the two groups is obvious （P〈0.05）. There were 5 cases with and one cases with grade 3 enteritis,in trial group;and 4 cases with viginal-rectal fistula and 1 case with grade 3 enteritis in the comparison group. The pelvic inplanted intensity modulated brachytherapy for the recurred cervical carcinoma is satisfactory in the short time curative effect. It is better than the routine brachytherapy. Its late effect is tolerable.

关 键 词：宫颈肿瘤/治疗 近距离放疗 调强放疗 放射疗法 

分 类 号：R737.33[医药卫生—肿瘤]