超声造影评价氩氦刀消融治疗肝脏恶性肿瘤的疗效  

Contrast-enhanced ultrasound evaluation of efficacy of argon-helium cryoablation in the treatment of liver malignancies

作　　者：崔伟珍[1] 陈焕伟 谢守松[1] 甄作均 张海雄 

机构地区：[1]广东省佛山市第一人民医院超声诊疗中心 [2]肝胆外科,广东佛山528000

出　　处：《中国介入影像与治疗学》2009年第6期533-536,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的探讨超声造影(CEUS)评价氩氦刀消融治疗肝癌局部疗效的意义。方法超声引导下对27例肝癌患者的27个病灶行氩氦刀消融治疗术,用CEUS评价其局部疗效;并以同期增强CT(CECT)作为对比。结果术后1个月复查CEUS示病灶完全消融21个(77.78%),不完全消融为6个(22.22%);CECT提示病灶完全消融为22个(81.48%),不完全消融5个(18.52%)。同CECT比较,CEUS的诊断敏感性、特异性、阳性预测值、阴性预测值、准确性分别为80.00%(4/5)、90.91%(20/22)、66.67%(4/6)、95.24%(20/21)和88.89%(24/27)。结论CEUS可作为评价氩氦刀消融治疗肝癌局部疗效的一种有效手段。Objective To observe the value of contrast-enhanced ultrasound（CEUS） in the evaluation of efficacy of Argon-Helium cryoablation therapy for liver malignancies.Methods A total of 27 patients with 27 lesions of liver malignancies underwent ultrasound-guided Argon-Helium cryoablation therapy.CEUS was used to evaluate the local response and compared with contrast-enhanced CT（CECT）.Results One month after Argon-Helium cryoablation therapy,21 lesions（77.78%） were diagnosed as complete ablation with CEUS and 22（81.48%） with CECT.Contrast enhancement within lesions was demonstrated in 6 lesions（22.22%） with CEUS and 5（18.52%） with CECT.As compared to CECT,the sensitivity,specificity,positive and negative predictive value,and accuracy of CEUS in diagnosing tumor residue 1 month after treatment was 80.00%（4/5）,90.91%（20/22）,66.67%（4/6）,95.24%（20/21）,and 88.89%（24/27）,respectively.Conclusion CEUS is an effective alternative for the evaluation of efficacy of Argon-Helium cryoablation in the treatment of liver malignancies.

关 键 词：超声造影 氩氦刀 肝肿瘤 疗效评价 

分 类 号：R735.7[医药卫生—肿瘤] R445.1[医药卫生—临床医学]