高露洁抗敏感牙膏改善牙本质敏感症的效果  

Effect of colgate anti-sensitive toothpaste on dental hypersensitiveness

作　　者：王洁[1] 赵蕾[1] 孟姝[1] 吴亚菲[1] 

机构地区：[1]四川大学华西口腔医学院,四川成都610041

出　　处：《牙体牙髓牙周病学杂志》2009年第11期658-661,共4页Chinese Journal of Conservative Dentistry

摘　　要：目的:评估无监督情况下家庭日常使用高露洁抗敏牙膏4周后牙本质过敏症状的改善情况。方法:本研究为单一产品、单盲、多中心的临床研究。采用数字化疼痛评判法(VAS)筛选受试者。通过普通牙膏洗脱2周去除干扰因素后,给予受试者高露洁抗敏牙膏和软毛牙刷,用VAS法分别于基线(VAS-1)和4周实验结束后(VAS-2)评估受试者牙本质敏感情况。结果:本研究共筛选1315人,纳入受试者210名,完成试验者193名,基线时VAS平均值为54.94±13.81;试验4周后VAS平均值为36.87±18.75,前后比较差异有统计学意义(P<0.001)。结论:日常使用高露洁抗敏感牙膏4周,对牙本质敏感症有一定的改善作用。AIM：To evaluate the effects of daily application of Colgate anti - sensitivity toothpaste on relieving dentinal hypersensitivity. METHODS： The study was a single -blind muhicentered clinical trial. Subjects, who were included by Visual Analog Scale （VAS） , undertook a washout period for 2 weeks by using Colgate non - sensitive toothpaste in order to eliminate interference factors. Then Colgate anti - sensitivity toothpaste and soft toothbrush were applied daily in next four weeks. The conditions of dentinal hypersensitivity were assessed by VAS at baseline and after 4 weeks. RESULTS：In total of 1315 individuals, 210 subjects participated and 193 were enrolled in the study. At the baseline, average VAS was 54.94 ±13.81 ; four weeks later, average VAS decreased to 36.87 ± 18.75. There was significant difference （P 〈0.001 ）. CONCLUSION： Colgate anti -sensitivity toothpaste can relieve dentinal hyper- sensitivity.

关 键 词：牙本质敏感 数字化疼痛评判法 牙膏 

分 类 号：R781.2[医药卫生—口腔医学]