功能性消化不良胆囊功能及其与胃排空相关性的初步探讨  

Motility of Gallbladder in Patients with Functional Dyspepsia

作　　者：蓝宇[1] 闫小兵[1] 李萍 甘毓鳞 

机构地区：[1]北京积水潭医院,北京100035

出　　处：《临床消化病杂志》1998年第3期117-119,共3页Chinese Journal of Clinical Gastroenterology

摘　　要：为了解功能性消化不良(Functional dyspepsia.FD)患者是否存在胆囊功能障碍及胆囊功能与胃运动功能之间的相关性,我们对16例FD患者及8名健康人进行了B超下胆囊功能测定及核素胃排空检查.结果显示:FD患者2小时胃排空率为56.38±14.93%,半排空时间为104.72±22.73min,正常人胃排空率为70.75±11.44%,半排空时间为83.60±19.99min.FD组的胃排空明显延迟(P<0.001).FD组胆囊排空率<30%者较正常人明显增多(P<0.05),而将FD组进一步分为胃排空异常及胃排空正常组后发现胃排空正常的FD病人胆囊功能与健康人无差异,而胃排空延迟的FD病人的胆囊排空率亦明显降低,与正常人及胃排空正常的FD病人相比均有显著差异(P<0.05).结果表明功能性消化不良患者有胆囊排空功能的减弱,这种减弱与胃排空功能障碍有关,其相关的机制有待于进一步研究.Objective: To investigate whether there is functional disorder of gallbladder in patients with functional dyspepsia (FD) and the relationship between motility of stomach and gallbladder. Mothods: 16 cases of FD patients, 8 healthy subjects (HS) were included. We masured the length, width and area index of gallbladder with ultrosouno-graphy, before and within 2 hours after fat meal, monitored solid gastric emptying with radioneuclide scinitography. Results: There were delayed gastric emptying in FD patients than in HS (gastric emptying rate was 56. 38% vs 70. 75%, P<0. 001, half emptying time was 99,97 min. vs83.60 min P<0.05). The maximun emptying rate of gallbladder <30% in 2 hours were in 6 cases of FD patients, but none in HS. Empyting rate of gallbladder in all HS were > 50 % . There was significance between two groups ( P < 0. 05). Conclusions: The patients with FD have delayed gallbladder emptying rate, this change might be related with delayed gastric emptying. The mechanisms of the relationship between gastric emptying and gallbladder function should be studied furtherly.

关 键 词：功能性 消化不良 胆囊排空功能 胃排空 核素显像 

分 类 号：R573.02[医药卫生—消化系统]