完全控制的支气管哮喘患者肺功能和气道高反应性测定  

Clinical significance of airway hyperresponsiveness in patients with totally controlled asthma

作　　者：袁竹青[1] 胡苏萍[1] 聂汉祥[1] 

机构地区：[1]武汉大学人民医院呼吸内科,武汉430060

出　　处：《临床肺科杂志》2010年第1期36-37,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的检测完全控制的支气管哮喘患者肺功能和气道反应,探讨其临床意义。方法选择71例完全控制的支气管哮喘患者,测定肺功能和气道反应性。选择30名急性发作期支气管哮喘患者和15名健康老年人作为对照。结果71例完全控制的支气管哮喘患者中,49例(84.5%)支气管激发试验阳性,9例(15.5%)支气管激发试验阴性。完全控制哮喘组和哮喘组患者FEV1占预计值%和FEV1/FVC分比较差异有统计学意义(P<0.01);完全控制哮喘组和健康对照组受试对象FEV1占预计值%和FEV1/FVC比较差异无统计学意义(P>0.05)。结论完全控制的支气管哮喘患者多数存在气道高反应性,测定患者气道反应性有助于指导哮喘治疗。Objective To investigate the clinical significance of airway hyperresponsiveness and lung unction. Methods Seventy-one patients with totally controlled asthma were selected. Bronchial provocation test and lung function were performed. 30 patients with asthma during the exacerbation period and 20 healthy subjects were selected as control. Results In 71 patients with totally controned asthma ,60（ 84. 5% ） showed positive bronchial provocation test and 11 （ 15.5% ） patients showed negative bronchial provocation test. There was no significant difference in FEV1% Pred and FEV1/FVC between the patients with totally controlled asthma and the healthy subjects （P 〉 0. 05 ）. Conclusion Airway hyperresponsiveness still exist in the patients with totally controlled asthma and it may be helpful to guild the treatment to determine airway hyperresponsiveness.

关 键 词：哮喘 气道高反应性 肺功能 

分 类 号：R562.25[医药卫生—呼吸系统]