稀释托品卡胺散瞳试验对诊断阿尔采木病的潜在价值  

The Potential Value of Dilute Solution of Tropicamide for Pupil Dilation Test in Diagnosing Patients with Alzheimer′s Disease/

作　　者：杨青[1,2] 杜桂来[1,2] 赵刚 朱天[1,2] 

机构地区：[1]四川生殖卫生学院医学系 [2]四川联合大学无线电电子学系

出　　处：《四川省卫生管理干部学院学报》1998年第3期134-135,共2页Journal of Sichuan Continuing Education College of Medical Sciences

摘　　要：目的：探讨稀释托品卡胺散瞳试验对诊断阿尔采木病潜在的临床意义。方法：１０９例老人按ＨＤＳ测查评分等级分为四组，进行０．０１％托品卡胺散瞳试验，观察瞳孔的改变。结果：各组受试者对托品卡胺散瞳呈现不同的敏感性反应，痴呆组和痴呆前期组瞳孔直径变化百分率之间关系密切，几乎呈相同形式，相反，痴呆组与正常组间扩瞳反应有显著性差异。结论：稀释托品卡胺散瞳试验对高危人群中阿尔采木病人的筛查具有参考价值。bjective:To　investigate　the　potentially　clinical　significance　of　dilute　solution　of　tropicamide　for　pupil　dilation　test　in　diagnosing　patients　with　Alzheimer′s　disease.Method:According　to　the　Grading　of　Hasegawa′s　Dementia　Scale(HDS),109　cases　of　aged　subjects　were　divided　into　four　groups　and　pupildilating　test　with　diluted　solution　of　tropicamide(0.01%)was　carried　out　for　them,observing　the　changes　of　pupils　closely.Results:There　were　different　responses　for　these　subjects　to　the　test:The　relationship　of　the　rate　in　percentage　of　the　changes　of　pupil　diameters　for　patients　with　Alzheimer′s　disease　and　for　those　with　prestage　of　the　disease　was　closely　related,showing　almost　the　same　patterns;in　contrast　the　pupil　response　for　patients　with　Alzheimer′s　disease　compared　to　the　control　group　showed　significantly　difference.Conclusion:The　pupildilating　test　of　the　diluted　tropicamide　solution　for　screening　of　high　risk　population　possibly　with　Alzheimer′s　disease　is　of　value　for　reference.

关 键 词：稀释托品卡胺 散瞳试验 阿尔采木病 诊断 

分 类 号：R773.04[医药卫生—眼科]