自体骨髓移植联合自体外周造血干细胞移植治疗恶性血液病  

COMBINATION AUTOLOGOUS BONE MARROW TRANSPLANTATION WITH PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR TREATMENT OF HEMATOLOGIC MALIGNANCIES

作　　者：苏力[1] 邵文硕[1] 崔小华[1] 甄少波[1] 徐娟[1] 荆华[1] 杨立[1] 李健[1] 李亚林[1] 田丁[1] 靳怀建 

机构地区：[1]首都医科大学附属宣武医院,北京市宣武区100053

出　　处：《白血病》1998年第3期149-151,共3页

摘　　要：联合应用自体骨髓移植和自体外造血于细胞移植治疗4例急性白血病患者和Z例非霍奇金淋巴瘤患者，采集PBSC的MNC计数为（0．82～2．4）×109／kg，CD34细胞数（1．23～3．6）×106／kg，骨髓细胞NC计数为（0．92～2．4）×108／kg，CD34细胞计数为（0．9～2．4）×106／kg，结果表明经上述治疗后患者造血及免疫功能恢复明显快于单独的移植治疗方法且毒副作用少。4 cases of acute myeloid leukemia and 2 cases of NHL were treated with autologous bone marrow transplantation (ABMT) combining with peripheral blood stem cell transplantation (APBSCT). The amount of (0. 82×108/kg^2. 4×106/kg) MNC and (l. 23 ×106/kg^3. 6×106/kg) CDbcell were collected from peripheral blood and 0. 92~2. 4×108/ kg of NC and 0. 9~2. 4×106/kg of CS+34cell collected from bone marrow were transfused to patients. The recovery days of WBC> 1. 0×109/L were + 15 (13^+20), of granulocyte> 0. 5×109/L were + 12 (+11^+17) and of platelate>20×109/L were + 19 (14~ + 29). The result showed more rapid reconstitution of hematopoiesis and less side effections by using this regimen.

关 键 词：自体骨髓移植 造血刺激因子 白血病 APBSCT 治疗 

分 类 号：R733.710.5[医药卫生—肿瘤]