1994～2007年北京市先天性甲状腺功能减低症的流行病学研究  

Epidemiological study of congenital hypothyroidism in Beijing from 1994 to 2007

作　　者：裘蕾[1] 安琳[1] 丁辉[2] 张玉敏[2] 

机构地区：[1]北京大学医学部公共卫生学院,北京100083 [2]首都医科大学附属北京妇产医院北京妇幼保健院,北京100026

出　　处：《中国儿童保健杂志》2009年第6期697-699,共3页Chinese Journal of Child Health Care

摘　　要：【目的】为了获得北京地区先天性甲状腺功能减低症(congenital hypothyroidism,CH)的流行病学分布特征。【方法】对北京市现有的新生儿疾病筛查相关报表和个案信息资料进行描述性分析和统计推断。【结果】14年中北京市确诊CH患儿336名,总患病率为0.28‰,并且患病率呈逐年上升的趋势;男性患病率为0.28‰,女性为0.42‰,男女患病率之比为1∶1.5;患儿中高龄产妇占11.8%,明显高于全部活产儿;未发现CH的患病率存在户籍、出生体重、分娩孕周等的差异。【结论】北京地区CH的患病率呈上升趋势,女性新生儿与高龄产妇分娩新生儿可能是CH的高发人群。[Objective] In order to obtain epidemiological distribution of congenital hypothyroidism（CH） in Beijing area. [Method] All statements related to neonatal screening and case information were made descriptive analysis and statistical inference. [Result] From 1994 to 2007, 336 children with CH were confirmed in Beijing, the total prevalence rate was 0. 28‰, the prevalence rate of CH was higher in female newborns（0. 42% ） than in male newborns（0.28% ）,the sex ratio was 1 ： 1.5. [Conclusion] The prevalence rate of CH shows upward trend in Beijing, the female newborns and those with older mothers may be the high-risk population of the CH.

关 键 词：先天性甲状腺功能减低症 流行病学分布 新生儿疾病筛查 

分 类 号：R725.8[医药卫生—儿科]