基于DNA双链特征的启动子预测方法  

Algorithm for Promoter Prediction Based on Double-Stranded Characteristics of DNA

作　　者：王雯雯[1] 武栓虎[1] 

机构地区：[1]烟台大学计算机学院,山东烟台264005

出　　处：《北京交通大学学报》2009年第6期124-127,共4页JOURNAL OF BEIJING JIAOTONG UNIVERSITY

基　　金：国家自然科学基金资助项目(60772028)

摘　　要：真核启动子预测是DNA序列分析的重要问题之一.本文提出一个基于内容的新算法,考虑DNA的双链特征,特征的出现频率用位置权矩阵表示,利用boosting算法进行训练和预测,得出的结果与其他算法相比,有很好的敏感性和特异性.The prediction of Eukaryotic promoter is one of the most important problems in DNA sequence analysis. In this work, we develop a new algorithm which is based on word considering the double-stranded characteristics of DNA. The frequency of occurrence of characteristics is represented by positional weight matrix. The boosting algorithm is used to train and predict respectively. The results in the algorithms have better sensitivity and specificity than that of the other algorithms.

关 键 词：启动子预测 DNA的双链特征 位置权矩阵 

分 类 号：TP391[自动化与计算机技术—计算机应用技术]