多序列MRI对超急性期脑出血诊断价值的实验研究  

The experimental study of a set of MRI sequences on applied values in hyperacute intracerebral hemorrhage

作　　者：詹茜[1] 翟建[1] 杨宏楷[2] 陈基明[1] 

机构地区：[1]皖南医学院弋矶山医院放射科,芜湖241001 [2]马鞍山市人民医院放射科,243000

出　　处：《安徽医学》2009年第11期1286-1289,共4页Anhui Medical Journal

摘　　要：目的探讨多序列MRI对超急性期脑出血的诊断价值。方法将20只健康大白兔随机分为脑出血A组(8只)、脑出血B组(8只)和对照组(4只),A、B两组分别在造模后1h和6h两个时间点进行SE-T1WI、FSE-T2WI、GRE-T2*WI、DWI和EPI-T2*WI扫描,对照组于1h和6h进行扫描。结果血肿在GRE-T2*WI、DWI和EPI-T2*WI上以低信号为主,在FSE-T2WI上为稍高信号,在SE-T1WI上为等信号;A、B两组血肿部分序列所测体积比较,差异有统计学意义(P<0.05)。结论GRE-T2*WI对超急性期血肿的诊断敏感性高,结合DWI和EPI-T2*WI等多序列,可为超急性期脑出血诊断和鉴别诊断提供一定的依据。Objective To explore the diagnostic value of a set of MRI sequences in hyperacute ICH and injury in perihematomal brain tissue.Methods 20 rabbits（mean body weight,2.0~2.5 kg） were divided randomly into ICH group A （n=8）、ICH group B （n=8）and control group （n=4） randomly.Animal models in group A and B were examined by a set of MRI sequences（SE-T1WI、FSE-T2WI、GRE-T2WI、DWI and EPI-T2WI） at the time of 1 hour and 6 hour after ICH models respectively.Results The hematomas were showed low signal in imagings of GRE-T2WI、DWI and EPI-T2WI,slightly high signal in imagings of FSE-T2WI,and iso-signal in magings of SE-T1WI;The volume of hematomas differed significantly in two group（P0.05）.Conclusion GRE-T2WI sequence in the diagnosis of hyperacute ICH showed high sensitivity.A set of MRI sequences scanning can be the way of diagnosing and differentiate diagnosing in hyperacute intracerebral hemorrhage.

关 键 词：脑出血 动物实验 磁共振 

分 类 号：R743.3[医药卫生—神经病学与精神病学]