Inverse computation for cardiac sources using single current dipole and current multipole models  

作　　者：王倩 马平 陆宏 唐雪正 华宁 唐发宽 

机构地区：[1]Department of Physics,State Key Laboratory for Artificial Microstructure and Mesoscopic Physics,Peking University [2]Department of Cardiology,the 309th Hospital of PLA

出　　处：《Chinese Physics B》2009年第12期5566-5574,共9页中国物理B（英文版）

基　　金：Project supported by the State Key Development Program for Basic Research of China (Grant No 2006CB601007);the National Natural Science Foundation of China (Grant No 10674006);the National High Technology Research and Development Program of China (Grant No 2007AA03Z238)

摘　　要：Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-square fit to the measurements using a simulated annealing algorithm. The measured signals are detected at 36 observation nodes by a superconducting quantum interference device （SQUID）. By studying the trends of position, orientation and magnitude of the single current dipole model and the current multipole model in the QRS complex during one time span and comparing the reconstructed magnetocardiography （MCG） of these two cardiac models, we find that the current multipole model is a more appropriate model to represent cardiac electrophysiological activity.Two cardiac functional models are constructed in this paper. One is a single current model and the other is a current multipole model. Parameters denoting the properties of these two models are calculated by a least-square fit to the measurements using a simulated annealing algorithm. The measured signals are detected at 36 observation nodes by a superconducting quantum interference device （SQUID）. By studying the trends of position, orientation and magnitude of the single current dipole model and the current multipole model in the QRS complex during one time span and comparing the reconstructed magnetocardiography （MCG） of these two cardiac models, we find that the current multipole model is a more appropriate model to represent cardiac electrophysiological activity.

关 键 词：MAGNETOCARDIOGRAPHY inverse computation cardiac source model 

分 类 号：R318.0[医药卫生—生物医学工程] O511[医药卫生—基础医学]