早发型重度子痫前期并发腹水的临床特点和对围产期结局的影响  

Clinical Characteristics of Early-onset Severe Pre-eclampsia with Ascites and the Effect to Pregnancy Outcome

作　　者：卢莉萍[1] 刘兰玉[1] 范立叶[1] 柴光兰[1] 

机构地区：[1]潍坊市妇幼保健院产科,山东潍坊261011

出　　处：《潍坊医学院学报》2009年第5期334-336,共3页Acta Academiae Medicinae Weifang

摘　　要：目的探讨早发型重度子痫前期并发腹水的临床特点和对国产期结局的影响。方法对127例早发型重度子痫前期患者的临床资料进行回顾性分析,根据有无并发腹水分为腹水组(30例)和非腹水组(97例),分析孕妇一般情况、分娩方式、并发症或合并症,两组围产儿不同胎龄(<30周,30～32周,32～34周)的围产儿结局。结果①腹水组产科并发症/合并症的发生率较无腹水组高(P<0.05),其中又以低蛋白血症、肝肾功能不全、HELLP综合征、产后出血为著。②腹水组不同胎龄围产儿病死率均高于同胎龄无腹水组(P<0.05),腹水组胎龄<32周的围产儿病死亡率与≥32周的比较,差异有统计学意义(P<0.05)。结论早发型重度子痫前期并发腹水发病早、并发症多,严重影响母儿健康。Objective To investigate the clinical characteristics of early-onset severe pre-eclampsia wiith ascites and the effect to pregnancy outcome. Methods A retrospective study was conducted on 127 Early-onset severe preeclampsia mothers who were divided into two groups ：30 complicated with ascites（ ascites group ） and 97 without （nonascites group ）. The general conditions, mode of delivery and complications were analyzed, the outcom of infants in both group within the same gestational age group were compared （ 〈 30 weeks, - 32 weeks, - 34 weeks ）. Results More complications were found in the ascites group than in the non-ascites group,especially the incidence of hypoproteinemia,liver and renal faliure and HELLP Syndrome. The mortality rate in the ascites group was all higher than that in the non-ascites group （ P 〈 0.05 ）. Conclusion The early onset of ascites and higher rate of complications in early-onset severe preeclamptic women implies the adverse maternal and fatal outcomes, ascite in early-onset severe pre-eclampsia cases should alert the clinicians, and timely treatment to reduce the incidence of complication, can avoid the adverse perinatal outcomes.

关 键 词：重度子痫前期 早发型 腹水 并发症 围产儿 

分 类 号：R742.1[医药卫生—神经病学与精神病学]