应激对缺锌和补锌大鼠脂质过氧化的影响  

EFFECTS OF STRESS ON LIPID PEROXIDATION OF ZINC- DEFICIENT AND ZINC-SUPPLEMENTARY RATS

作　　者：蒋与刚[1] 程义勇[1] 王冬兰[1] 刘继鹏[1] 

机构地区：[1]军事医学科学院卫生学环境医学研究所

出　　处：《解放军预防医学杂志》1998年第4期263-265,共3页Journal of Preventive Medicine of Chinese People's Liberation Army

基　　金：国家自然科学基金

摘　　要：以电击和束缚两种方式建立动物应激模型，观察应激因素对缺锌和补锌大鼠脂质过氧化的影响。结果表明，无论接受电击或束缚应激，缺锌大鼠血浆及肝脏ＬＰＯ含量均显著升高（Ｐ＜０．０１），亦高于补锌动物；接受电击的大鼠肝脏ＭＴ含量显著增加（Ｐ＜０．０１），补锌后增加更明显。结果提示，电击或束缚应激可增强大鼠的脂质过氧化反应。The effects of stress on lipid peroxidation were observed in zinc-deficient and zinc-supplementary rats,under the conditions of electric shock or bind. The results showed that the concentrations of plasma and liver LPO in zinc-deficient rats were significantly increased (P<0.01),and higher than the zinc-supplementary group.The contents of MT in liver were markedly increased when given shock stimulation (P<0.01) and were further increased after zinc supplementation. The findings indicated that zinc supplementation might decrease the oxidative damage of stress.

关 键 词：锌营养 应激 脂质过氧化 锌 锌缺乏 

分 类 号：R591.1[医药卫生—内科学] R977.9[医药卫生—临床医学]