妥布霉素产生菌激光育种的研究  

Study on Selection Producing Strain of Tobramycin by Laser

作　　者：王凤仙[1,2,3,4] 吴振倡 陈守川 谢长洲[1,2,3,4] 詹佩君 白骅 

机构地区：[1]浙江省医学科学院药物所 [2]浙江省微生物研究所 [3]浙江大学物理系 [4]浙江海门制药厂

出　　处：《生物学杂志》1998年第4期15-16,共2页Journal of Biology

摘　　要：本文首次报道铜蒸气激光选育妥布霉素产生菌—黑暗链霉菌（Ｓｔｒｅｐｔｏｍｙｃｅｓｔｅｎｅｂｒａｒｉｕｓ）的研究结果。在相同实验条件下，铜蒸气激光辐照黑暗链霉菌比其随后又以氯化锂复合处理的选育效果好。在铜蒸气激光辐照后，曾获得实验高产株，发酵单位比对照未辐照组提高７２％。The paper reported first about the study of selection with copper vapor laser in Streptomyces tenebrarius.Under identical experimental conditions,the radiation with copper vapor lasor is better than that with copper vapor laser followed by lithium chloride treatment.Experimental highproductive strain was obtained after radiation with copper vapor laser.Its unit of fermentation was increased 7.2% as compared with the control. Whether it is caused by repair or by immediate action of lithium chloride,or the lithium chloride increases the activities of cell repair systems in streptomyces tenebrarius,depends on further discussion.

关 键 词：妥布霉素 黑暗链霉菌 铜蒸气激光 氯化锂 选育 

分 类 号：Q939.13[生物学—微生物学] TQ465.92[化学工程—制药化工]