多发性骨髓瘤并发肾功能不全48例临床分析  

作　　者：傅槟槟[1] 万建新[1] 陈君敏[2] 

机构地区：[1]福建医科大学附属第一医院肾内科,福建福州350005 [2]福建医科大学附属第一医院血液内科,福建福州350005

出　　处：《中外医疗》2009年第36期4-5,共2页China & Foreign Medical Treatment

摘　　要：目的研究多发性骨髓瘤(MM)并发肾功能不全的临床特点及治疗措施。方法回顾性分析48例MM并发肾功能不全患者临床资料。结果予以化疗及保护肾脏等综合治疗,化疗有效患者肾功能逆转率为78.1%,化疗无效患者肾功能逆转率为31.25%,总逆转率为62.5%。结论MM并发肾功能不全临床表现复杂,有效的化疗、降血钙、碱化尿液、血液透析、避免应用肾毒性药物等综合治疗措施,可改善MM合并肾功能不全的预后。Objective To study the clinical features and therapeutic measures of patients with multiple myeloma（MM） accompanied renal insufficiency.Methods The clinical data of 48 patients with MM accompanied renal insufficiency were retrospectively analysed. Results To be chemotherapy and protect the kidneys and other comprehensive treatment, chemotherapy effective reversal of the rate of renal function in patients was 78.1%,chemotherapy ineffective reversal rate of renal function was 31.25% and the total reversal rate was 62.5%.Conclusion MM accompanied renal insufficiency complicated by the complex clinical manifestations and from these comprehensive treatments measures such as effective chemotherapy,lowering serum calcium, alkaline urine, hemodialysis and to avoid the application of renal toxicity of drugs can improve the prognosis of MM accompanied renal insufficiency.

关 键 词：多发性骨髓瘤 肾功能不全 

分 类 号：R738[医药卫生—肿瘤]