胃肠道间质瘤多层螺旋CT特点与恶性分级相关性研究  

Study on the MSCT features of GIST and the correlation study of malignancy grade

作　　者：赵艳萍[1,2] 文智[2] 刘文亚[1] 阿里甫.依马木 马继文[2] 贾志强[2] 

机构地区：[1]新疆医科大学第一附属医院影像中心 [2]新疆医科大学附属肿瘤医院CT室,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2009年第12期1728-1731,共4页Journal of Xinjiang Medical University

摘　　要：目的:探讨胃肠道间质瘤(GIST)的多层螺旋CT征象与恶性分级的相关性。方法:回顾性分析64例胃肠道间质瘤的资料,所有病例均行多层螺旋CT平扫及增强扫描,并经病理免疫组织化学检查证实。结果:间质瘤以胃部多见,占62.50%(40/64),其次为小肠,占18.75%(12/64)。GIST多表现为类圆形实性,边界清楚(47/64),以外生性生长为主(32/64)。密度多不均匀,坏死(47/64)、溃疡(31/64)常见,以不均匀强化、延迟强化为主。肝脏和腹腔为主要转移部位,转移灶坏死常见,也呈延迟强化。11例GIST伴发其他肿瘤。GIST的部位、坏死与溃疡的存在、强化方式及转移灶的有无与恶性分级呈正相关(P<0.05)。结论:胃肠道间质瘤的螺旋CT表现具有一定特征,并且不均匀强化方式,CT图像上坏死与溃疡的检出、转移灶的出现以及发生部位有助于对恶性间质瘤的判定。Objective： To discuss the sign of gastrointestinal stromal tumors（GISTs）in spiral CT and to a- nalysis its malignancy grade. Methods： Sixty-four cases of GISTs were analyzed retrospectively, all were checked by multi- slice spiral CT plain and enhancement scanning, and had immunity histochemistry con- firmation. Results： The tumors were more in the stomach （40/64）, the stomach body （n = 16） and the fundus （n = 11）, and then in intestine （12/64）. Most GIST were heterogeneous solid mass with clear boundary （47/64）, exophytic growth （32/64）, and always had necrosis （47/64） and ulcer （31/64）, which had nonuniform strengthen, especially in delayed enhancement. Liver （11/13） and peritoneal （5/13） were the more likely metastatic sites. 11 cases were accompanied with other tumors. GIST size, with necrosis and ulcer, non-uniform strengthen and had metastatic location had positive relationship with malignancyo（P 〈0.05）. Conclusion： GIST has some characteristic findings in Spiral CT. Some CT features maybe helpful in analysis of GIST malignancy grade.

关 键 词：胃肠道间质瘤 X线计算机 恶性分级 

分 类 号：R735.2[医药卫生—肿瘤] R735.3[医药卫生—临床医学]