肝癌经导管肝动脉化疗栓塞后Ⅱ期切除的远期疗效分析  

ANALYSIS OF THE SECONDARY RESECTION EFFECT OF HEPATOCELLULAR CARCINOMA AFTER TAE

作　　者：王小林[1] 龚高全[1] 程洁敏[1] 颜志平[1] 李茂全[1] 王建华[1] 

机构地区：[1]上海医科大学中山医院放射科

出　　处：《上海医科大学学报》1998年第5期335-335,339,共2页Journal of Fudan University(Medical Science)

摘　　要：目的中晚期肝癌经皮穿刺肝动脉化疗栓塞术（ＴＡＥ）后，为提高术后生存期，提供Ⅱ期切除术最佳指征。方法收集６２例中晚期肝癌经ＴＡＥ后Ⅱ期手术切除完整随访资料，分为未复发组（Ａ）、复发组（Ｂ）、以术前ＴＡＥ次数、间隔时间、ＡＦＰ变化、肝硬化程度、术前ＣＴ检查影像学改变、术后病理标本资料，采用相应统计方法进行统计分析。结果Ａ组术后生存率明显优于Ｂ组，Ａ组病人对ＴＡＥ反应、肿瘤大小和肝内子结节数等均优于Ｂ组。结论ＴＡＥ后肝肿瘤内碘化油沉积良好，肿瘤缩小达１／４～１／２以上，肝内无播散灶的病人Ⅱ期切除后复发率低。PURPOSE To evaluate the more suitable indication of secondary resection after hepatic arterial chemoembolization(HAE) for patients with hepatocellular carcinoma(HCC). METHODS Sixty-two patients treated by TAE and sequential resection were divided into two groups, the no recurrence group (group A), and the recurrence group (group B). Statistical comparisons were made by Student's T-test and Chi-squre methods. RESULTS The prognosis of the group A was better than that of the group B. The difference between the two groups was significant. The reaction to TAE, the tumor size and the number of intrahepatic metastatic focus before operation were decreased ( P<0.05 ). There was no obvious correlation with TAE times, interval of TAE and also the level of AFP changes ( P >0.05). CONCLUSIONS The results suggest that the complete accumulation of iodized oil in the tumor marked decreace in tumor size after TAE and no intrahepatic metastatic are the secondary resection indication. TAE treatment should be performed no more than four times before resection and the interval between the final TAE and resection be no longer than four months.

关 键 词：肝肿瘤 TAE 栓塞疗法 切除术 手术适应性 

分 类 号：R735.705[医药卫生—肿瘤]