MR血管成像与动脉质子自旋标记探讨脑血流异常与短暂性脑缺血发作的关系  

MR angiography and arterial spin labeling proton in assessing correlation between transient ischemic attack and intracranial artery perfusion abnormalities

作　　者：张丽雅[1] 高志翔[1] 周旭峰[1] 卢超[1] 白喜恩[1] 刘晓萍[1] 

机构地区：[1]洛阳市中心医院磁共振室,河南洛阳471009

出　　处：《中国医学影像技术》2009年第12期2190-2192,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨磁共振血管成像(MRA)与动脉质子自旋标记(ASL)在评价血流异常与颈内动脉系统短暂性脑缺血发作(TIA)关系中的应用价值。方法根据TIA发作频率将58例临床确诊的颈内动脉系统TIA患者分为单发组(12例)和频发组(46例)。所有患者均接受MRA和ASL成像,评价TIA患者颅内动脉狭窄及脑灌注状况。结果频发组发生血管狭窄合并ASL异常的患者33例(71.74%),单发组1例(8.33%)。TIA频发患者血管狭窄合并ASL异常发生率高于单发患者(P<0.05)。结论血管狭窄合并灌注异常是TIA频发发作的最重要因素之一。MRA与ASL联合运用,可一次完成血管狭窄及灌注异常的诊断,对确定TIA发作原因、判断预后提供帮助。Objective To assess the value of magnetic resonance angiography（MRA） and arterial proton spin labeling（ASL） in the internal carotid artery transient ischemic attack.Methods According to TIA seizure frequency,58 patients clinical diagnosed as TIA were divided into single group（n=12） and the frequent group（n=46）.All patients underwent MRA and ASL,then intracranial arterial stenosis and cerebral perfusion were evaluated.Results Vascular stenosis with abnormal ASL were detected in 33（71.74%） of 46 frequent TIA patients and 1（8.33%） single TIA patient.The incidence of vascular stenosis with abnormal ASL was higher in frequent TIA than that in single TIA（P〈0.05）.Conclusion Vascular stenosis with perfusion abnormality is one of the most risk factors of TIA frequent seizures.Combination of MRA and ASL can make judgment for stenosis and abnormality of cerebral blood flow,being helpful to understand the onset causes and prognosis of TIA.

关 键 词：脑缺血发作 短暂性 磁共振血管成像 灌注成像 

分 类 号：R743.31[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]