正常房水在活体对角膜移植免疫排斥反应的抑制作用  

Normal Aqueous Humor can Prevent Rejection of Orthotopic Corneal Allografts in Rabbits

作　　者：林白霜[1] 李志杰[2] 李辰[3] 

机构地区：[1]暨南大学医学院病理生理教研室,510632 [2]暨南大学组织移植与免疫中心 [3]暨南大学医学院眼科学教研室

出　　处：《广东医学》1998年第11期818-819,共2页Guangdong Medical Journal

摘　　要：目的：观察正常房水对角膜移植免疫排斥反应的作用。方法：在兔眼建立偏中心穿透性角膜移植模型，术后结膜下注射正常牛眼房水，观察植片存活时间。结果：与对照组相比，治疗组角膜移植对存活时间显著延长（P＜0.02）。结论：正常房水在活体内具有抑制角膜移植免疫排斥反应的作用。Objective: To test the in vivo immunosuppressive properties of aqueous humor. Methods: The eccentricallypenetrating keratoplasties were perfomed on New Zealand albino rabbits. using Japan rabbits as donor. Twelv recipient rabbitswere randomly allocated into 2 groups. The treatment grouprecevied subconjunctivally fresh aqueous humox from bovine eyes. Thecontrol grouprecived physiologic saline in a same way. Results: The results show that aqueous humor significantly prologed thegraft survival (P<0.02). Conclusion: the findings indicate that normal constituents of aqueous humor possess the capacity to prevent corneal graft refection.

关 键 词：角膜移植 房水 免疫排斥反应 

分 类 号：R779.65[医药卫生—眼科] R392.4[医药卫生—临床医学]