结直肠癌旁肿瘤沉积的研究进展  

Advances in research on pericolonic tumor deposits in colorectal cancer

作　　者：梁冀望[1] 王振宁[1] 宋永喜[1] 徐惠绵[1] 

机构地区：[1]中国医科大学附属第一医院肿瘤外科中国医科大学附属第一医院普通外科教研室胃肠肿瘤外科,辽宁省沈阳市110001

出　　处：《世界华人消化杂志》2009年第35期3620-3622,共3页World Chinese Journal of Digestology

基　　金：教育部新世纪优秀人才支持计划基金资助项目;No.NCET-06-0296;高等学校博士学科点专项科研基金资助项目;No.200801590006~~

摘　　要：结直肠癌的临床研究发现一些患者常存在结肠旁肿瘤沉积(PTDs),他有别于淋巴结转移癌,通常沿着血管周围,神经周围或者血管内生长.PTDs的特性及其与预后的相关性引起了学者们的广泛关注.本文综述了PTDs的生长与组织结构特点,在TNM分期中价值,提示其在结直肠癌病理及生物学行为方面的重要价值,并可能成为评估预后,制定个体化治疗方案的指标.Clinical studies have shown that pericolonic tumor deposits （PTDs） may develop in some patients with colorectal cancer. PTDs are different from lymph node metastases and are usually located along the perivascular, perineural or intravascular spaces. The characteristics of PTDs and their relationship with colorectal cancer prognosis have attracted wide attention. In this article, we will review the recent advances in research on PTDs in colorectal cancer with regard to their location and structural characteristics and their value in TNM staging. Moreover, we will highlight their important value in prediction of the biological behavior and pathology of colorectal cancer, and their potential use as a parameter for evaluation of prognosis and development of individualized treatment.

关 键 词：结肠旁肿瘤沉积 结肠癌 淋巴结转移 预后意义 

分 类 号：R735.3[医药卫生—肿瘤] R730.53[医药卫生—临床医学]