茶抗龋的动物模型  

ANTICARIES ANIMAL MODEL OF TEA

作　　者：曹进[1,2] 陈罕[1,2] 赵燕[1,2] 刘箭卫 沈乃[1,2] 

机构地区：[1]湖南医科大学 [2]湖北医科大学口腔医学院

出　　处：《营养学报》1998年第3期356-360,共5页Acta Nutrimenta Sinica

摘　　要：方法：用变形链球菌Ｉｎｇｂｒｉｔ在Ｗｉｓｔａｒ大鼠上复制出龋齿动物模型，以０．０２１ｍｍｏｌ／Ｌ氟化钠水作为阴性对照，０．０５３ｍｍｏｌ／Ｌ氟化钠水作为阳性对照，给龋模型鼠饲以不同氟浓度（０．０２３ｍｍｏｌ／Ｌ，０．０４２ｍｍｏｌ／Ｌ，０．０５６ｍｍｏｌ／Ｌ）茶水，以Ｋｅｙｅｓ龋齿计分标准和光镜观察作为评价指标，并用扫描电镜，电子能谱观察了茶的抗龋和对釉质龋的再矿化作用。结果：不同浓度的绿茶水均可显著降低龋齿的计分（Ｐ＜０．０１）。Caries model was successfully produced in Sprague Dawley gnotobiotic rats by using S.mutans Ingbritt.Rats were fed by tea water with different fluoride concentration (0.023, 0.042,0.056mmol/L) and 0.053mmol/L sodium fluoride was as used positive control and 0.021 mmol/L sodium fluoride as negative control.Keyes caries scores were observed under dissecting microscope.The anticaries and remineralization effect of tea was observed by electron scanning microscope and energy spectrum. Significantly lower caries scores were observed in the rats fed by green tea water(P<0.01) and the remineralization of enamel caries region was also observed.

关 键 词：茶 龋病 动物模型 再矿化 预防 

分 类 号：R781.01[医药卫生—口腔医学]