E-白藜芦醇的全合成  

Total Synthesis of(E)-Resveratrol

作　　者：吴爱群[1] 申利群[1] 吴志鸿[1] 

机构地区：[1]河池学院,广西宜州546300

出　　处：《时珍国医国药》2010年第1期75-76,共2页Lishizhen Medicine and Materia Medica Research

基　　金：广西自然科学基金(No.0899025);广西高校重点建设实验室-桂西北特色资源研究与开发实验室资助项目(No.[2006]4)

摘　　要：目的天然产物白藜芦醇的全合成。方法锂卤交换反应。结果以3,5-二甲氧基苯甲酸为原料,合成了天然产物E-白藜芦醇,总收率为38.6%,产品的结构经1H HMR、高分辨质谱确证。结论该方法具有原料易得,合成路线短,操作简便等优点。Objective To synthesize the E - resveratrol. Methods The lithium - halogen exchange reaction. Results The E - resveratrol was synthesized from 3, 5 - dimethoxybenzoic acid. The structure of the target product was confirmed by ^1 H NMR and HRMS. Conclusion This method has the advantage of accessible materials, short synthetic method and easy preparation.

关 键 词：白藜芦醇 全合成 

分 类 号：R284.2[医药卫生—中药学]