活血化瘀早期治疗中小量脑出血临床研究  

A Clinical Observation on Application of Huoxuehuayu Therapy for Early Stage of Moderate and Small Volume Intracerebral Hemorrhage

作　　者：原爱中[1] 姚小军[1] 文军宝[1] 梁爱堂 许勇[1] 白冬梅[1] 

机构地区：[1]解放军第22医院,青海格尔木816000

出　　处：《临床军医杂志》2009年第6期1019-1021,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨早期活血化瘀治疗脑出血对血肿吸收速度、血肿周围低密度区改变和神经功能恢复的影响。方法将出血部位及出血量相类似的86例脑出血患者随机分为治疗组（43例）和对照组（43例）。治疗组在常规治疗基础上早期给予复方丹参注射液10-20 m l,1次/d静滴,连用14-24 d。于治疗前、治疗后第5,14,24天行头颅CT动态观察分析测量血肿体积,血肿周围低密度区改变,血肿吸收后所留中风囊及神经功能采用N IHSS进行评价。结果治疗组血肿平均吸收速度明显快于对照组（P〈0.01）。与对照组相比,第14、24天治疗组血肿体积、血肿周围低密度区缩小（P〈0.01）,血肿吸收后所留中风囊平均面积,治疗组小于对照组（P〈0.05）。结论中小量脑出血早期采用活血化瘀治疗能促进血肿吸收,血肿周围低密度区缩小和神经功能改善。Objective To investigate the effection on the speed of hematoma absorption、the change of isehemic penumbra、nerve functional recovery and its mechanism by huoxuehuayu therapy in treating intracerebral hemorrhage（ICH）.Methods Eighty-six cases of acute stage of ICH confirmed by CT with similar hemorrhagic position and quantity were randomly divided into two groups.The treatment group（43 cases） was treated by routine comprehensive treatment added with Ⅳ drips of Fufang Danshen injection（10-20ml,once per day） and the control group（43 cases） by routine western medicine.Observe and investigate the all patients＇s cranial CT ambulatorily at day 5、day 14 and day 24 after treatment.Nerve functional recovery was evaluated by NIHSS.Results The hematoma of the treatment group was absorbed more quickly than the control group（P〈0.01） and the isehemic penumbra of the treatment group become more smaller（P〈0.01）.The scoring of neural dysfunction after treatment was significantly different between 2 groups（P〈0.05）.Conclusion Early huoxuehuayu therapy may accelerate the hematoma of cerebral hemorrhage patients to be absorbed quickly and diminish the isehemic penumbra.Therefore,improve the nerve function.

关 键 词：脑出血 活血化瘀 头颅CT 

分 类 号：R743.34[医药卫生—神经病学与精神病学]