2450MHz食管腔内微波辐射器热分布的在体研究  

Temperature distribution of 2450MHz microwave intracavitary applicator for esophagus in patients

作　　者：祁超[1,2] 苏国荣[1,2] 王保胜[1,2] 李鼎九[1,2] 卫功铨[1,2] 桑玫[1,2] 

机构地区：[1]河南省肿瘤医院放疗科 [2]河南省肿瘤医院胸外科

出　　处：《中华放射肿瘤学杂志》1998年第3期159-161,共3页Chinese Journal of Radiation Oncology

摘　　要：目的研究２４５０ＭＨｚ食管腔内微波辐射器在人体内热分布情况。材料与方法通过５例食管癌病人开胸术中进行食管内辐射器加温并在壁内不同深度测温并与管腔内温度进行对照得出食管壁不同深度的温升情况。结果在腔内温度维持４５℃左右时，辐射器有效加温长度中心深０．５ｃｍ、１ｃｍ处温度约在４１℃和３９℃，从表面往深度去的温降呈指数下降，比理论计算值（０．５ｃｍ３８．０℃，１ｃｍ３７．４℃）要好得多。结论２４５０ＭＨｚ食管腔内辐射器在深部温降呈指数型，０．２５ｃｍ，０．５ｃｍ，１ｃｍ深度温度与表面温度（０ｃｍ）之差分别为２℃、４℃及６℃。Purpose To determine the temperature distribution in various depths of esophagus by 2450MHz microwave intracavitary applicator in patients.Materials and Methods Five patients with esophageal carcinomas were entered in this study. At the beginning of the thoracotomy, an applicator with a thermosensor on its surface was put into the esophageal cavity and adjusted. The thermosensor was placed at the center of the lesion. Another two thermosensors were inserted into the cancer mass on esophageal wall from the opened chest cavity measuring the temperatures at different depth.Results When the intraluminal temperature at about 45℃ was maintained,temperatures at depth of 0.5 and 1.0cm in the wall were about 41℃ and 39℃. The temperature gradient revealed a exponential curve, but they were better than the theoretically calculated curve (38.0℃ and 37.4℃ at the 0.5cm and 1cm). The possible explanations was the transmission and cooling of the mucosa by the submucosal plexus.Conclusion The temperature gradient in human esophageal wall appears to be exponential for 2450 MHz microwave applicator. The temperature falling at 0.25,0.5 and 1cm is about 2℃,4℃and 6℃ accordingly.

关 键 词：腔内微波辐射器 食管癌 微波疗法 热分布 

分 类 号：R735.105[医药卫生—肿瘤]