慢性酒精中毒性精神障碍患者周围神经系统临床电生理研究  

A CLINICAL AND ELECTROPHYSIOLOGICAL STUDY ON PERIPHERAL NERVOUS SYSTEM OF PATIENTS WITH MENTAL DISORDER ATTRIBUTED TO CHRONIC ALCOHOLISM

作　　者：李传平[1] 刘华[1] 

机构地区：[1]山东省安康医院,济宁272051

出　　处：《中国药物依赖性杂志》2009年第6期467-469,477,共4页Chinese Journal of Drug Dependence

摘　　要：目的:探讨慢性酒精中毒性精神障碍患者周围神经系统的电生理改变。方法:对178例慢性酒精中毒性精神障碍患者进行电生理检查,观察肌电图(EMG)、运动神经传导速度(MCV)和感觉传导速度(SCV)的变化情况。结果:178例患者电生理检查结果提示有神经源性损害,上下肢EMG异常差异无显著性(P>0.05),SCV和MCV较对照组均有不同程度的减慢,而SCV的改变更加明显;SCV异常率为81.83%,且异常程度与饮酒年限呈正相关(P<0.05);28例双上肢无临床症状的患者中,12例尺神经MCV、SCV有改变。结论:慢性酒精中毒性精神障碍患者的周围神经有神经源性损害。Objective：To explore the electrophysiological change of peripheral nervous system of patients with mental disorder attributed to chronic alcoholism.Methods：Through electrophysiological examination into 178 patients who suffered from chronic alcoholism,we observed the changes of their electromyogram（EMG）,motorius conduction velocity（MCV）and sense conduction velocity（SCV）.Results：The electrophysiological examination of the 178 patients indicated that their neurons were harmed.There were no obvious differences in EMG between upper and lower limbs（P0.05）.In comparison with the control group,SCV and MCV slowed down in some degree,and the change of SCV was more evident;the rate of abnormity was 81.83%,and the degree of abnormity was proportional to the length of drinking history（P0.05）;among the 28 patients whose upper limbs had no clinical symptoms,there were 10 patients whose MCV and SCV of the ulnar nerves had some changes.Conclusion：The peripheral nervous system of patients with mental disorder attributed to chronic alcoholism is harmed in neurons.

关 键 词：慢性酒中毒 精神障碍 周围神经 神经电生理 

分 类 号：R749[医药卫生—神经病学与精神病学] R651.3[医药卫生—临床医学]