冷循环微波聚能刀治疗原发性肝癌临床疗效观察  

Clinical Efficacy of Cool-Needle Microwave Coagulation Treatment (MCT) versus Hepatectomy in Primary Carcinoma of Liver

作　　者：张玉斌[1] 李振符[1] 谷建斌[1] 王岩[1] 张景承[1] 耿蕴峰 

机构地区：[1]石家庄市第一医院肝胆外科,石家庄050011

出　　处：《临床误诊误治》2010年第1期46-48,共3页Clinical Misdiagnosis & Mistherapy

摘　　要：目的评价冷循环微波聚能刀(MCT)治疗原发性肝癌的临床疗效。方法选择2006年6月～2009年8月我院收治的原发性肝癌225例,按照住院号奇偶数随机分为两组。微波组109例,在CT、B超或腹腔镜引导下行MCT治疗;开腹组116例,全麻下行肝切除术。比较两组手术时间、术中出血量、术后并发症、术后住院时间及复发率。结果微波组手术时间平均(35.5±6.7)min,开腹组平均(122.7±10.6)min;微波组术中出血量平均(1.2±0.6)ml,开腹组平均(358.3±40.1)ml,最多达1800ml;微波组术后住院时间平均(1.4±0.45)d,开腹组平均(11.2±1.7)d;两组比较差异均有统计学意义(P<0.05)。术后中位随访时间18个月,两组生存率分别为82.57%和83.62%,复发率分别为22.33%和21.15%,两组比较差异均无统计学意义(P>0.05)。结论与开腹肝切除术比较,MCT治疗原发性肝癌能最大限度的减小手术创伤与出血,全身反应轻微,术后恢复快,并能取得和开腹手术同样的近中期效果。Objective To evaluate the clinical effectiveness of cool-needle microwave coagulation treatment （MCT） in primary carcinoma of liver. Methods 225 patients of primary liver cancer,were chosen; 109 by MCT with ultrasonic or CT or laparoscope orientation （ group A） and 116 by hepatectomy （group B）. The age, sex, tumor size between group A and B is not statistically significant. Results The operation time of group A, B was 20-70 （35.5 ±6.7） rain vs 75-320 （122.7 ± 10. 6） min （P 〈0. 05）. The bleeding amount was 0-5 （1.2 ±0.6） ml vs 100-1800 （358.3 ±40.1） ml （P〈0.05）. Length of hospital stay was 1-3 （1.4±0.45） d vs 9-16 （11.2±1.7） d （P〈0.05）. All the differences was statistically significant. During a median follow-up of 18 months the survival rate was 82.57% vs 83.62% （P 〉0. 05） , the relapse rate was 22. 33% vs 21.15% （P 〉0. 05）. The difference was not statistically significant. Conclusion Compared with hepatectomy, MCT can minimize surgical trauma, bleeding and systemic reaction slightly, ensure rapid postoperative recovery and obtain the same effectiveness with ooen surgery.

关 键 词：癌 肝细胞 冷循环微波聚能刀 肝切除术 腹腔镜 

分 类 号：R735.7[医药卫生—肿瘤]