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作 者:李勇[1] 马红冰[1] 王培[1] 刘伟超[1] 施巩宁[1]
出 处:《中国综合临床》2010年第1期64-66,共3页Clinical Medicine of China
摘 要:目的探讨横结肠代食管不同手术路径对围手术期呼吸功能的影响。方法2004年5月至2008年6月食管癌切除横结肠代食管患者40例,经胸骨后颈部吻合20例(胸骨后组),经食管床颈部吻合20例(食管床组)。监测两组患者术后呼吸功能及血气分析主要指标。结果胸骨后组术后肺活量占预计值百分比(VC%)[第5、7、10、14天分别为(42.17±10.15)%、(49.52±9.56)%、(55.67±10.73)%、(60.27±10.52)%]与食管床组[第5、7、10、14天分别为(37.65±9.52)%、(40.72±10.12)%、(47.02±10.65)%、(52.89±10.82)%]相比差异均有统计学意义(P均〈0.05);胸骨后组术后第1秒用力呼气量占预计值百分比(FEV1%)[第10、14天分别为(60.55±16.71)%、(67.12±16.90)%]与食管床组[第10、14天分别为(45.23±16.26)%、(50.52±16.72)%]相比差异均有统计学意义(P均〈0.05);胸骨后组术后PaO2[第1、2、3、5、7、10、14天分别为(17.56±7.32)、(19.67±6.08)、(17.17±4.85)、(15.43±5.02)、(11.32±3.79)、(9.67±2.87)、(6.98±3.26)mmHg]与食管床组[术后第1、2、3、5、7、10、14天分别为(20.17±7.04)、(22.83±6.75)、(20.67±4.31)、(18.32±4.85)、(16.02±3.71)、(13.44±2.56)、(9.01±3.17)mmHg]比较,差异均有统计学意义(P均〈0.05)。结论食管癌切除术后,经食管床颈部吻合较经胸骨后颈部吻合对围手术期呼吸功能的影响更大。Objective To explore the effects of different operations on respiratory function after colon replacement for esophageal cancer. Methods Fourty patients with esophageal cancer underwent esophageetomy from May 2004 to June 2008 ,were retrospectively analyzed. The site of esophageal anastomosis was at neck after sternum in 20 cases, at neck through esophageal bed in other 20 cases. Blood gas analysis and pulmonary function were monitored in these patients before operation and in 14 days after operation. Results VC% were ( 42.17 ± 10.15 ) % (49.52 ±9.56)% ,(55.67 ± 10.73)% ,(60.27 ± 10.52)% in patients after sternum and (37.65 ±9.52)%, (40.72 ± 10.12) %, (47.02 ± 10.65 )%, (52.89 ± 10.82)% in patients through esophageal bed in 5th,7th, 10th, 14th postoperative day with significant statistical difference; FEV1% were (60.55 ± 16.71 ) %, (67.12 ± 16.90) % in patients after sternum and (45.23 ± 16.26)% 、 (50.52 ± 16.72)% in patients through esophageal bed in 10th, 14th postoperative day with significant statistieal difference ; Pan2 were ( 17.56 ± 7.32 ) mm Hg、 ( 19.67 ± 6.08 )mm Hg, (17.17 ± 4. 85 ) mm Hg,(15.43 ±5.02)mm Hg,(11.32±3.79)mm Hg、(9.67 ±2.87)mm Hg,(6.98± 3.26 ) mm Hg in patients after sternum and ( 20.17 ± 7.04 ) mm Hg, ( 22.83 ± 6.75 )mm Hg, ( 20.67 ± 4.31 ) mm Hg,(18.32 ±4.85)mm Hg、(16.02±3.71)mm Hg,(13.44 ±2.56)mm Hg、(9.01 ±3.17)mm Hg in patients through esophageal bed in 1 st,2nd,3rd,5th,7th,10th, 14th postoperative day with significant statistieal differenee. Conclusions After esophagectomy,esophageal anastomosis through esophageal bed has significant negative effect on respiratory function.
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