眼附属器黏膜相关淋巴瘤感染性因素研究进展  

Investigative progress of infectious agents in the mucosa-associated lymphoid tissue lymphomas of ocular adnexa

作　　者：马小梅[1] 刘惠敏[1] 李玉珍[2] 

机构地区：[1]第二军医大学附属长征医院病理科,上海200003 [2]第二军医大学附属长征医院眼科,上海200003

出　　处：《眼科研究》2010年第1期90-92,共3页Chinese Ophthalmic Research

摘　　要：感染性因素与人类恶性肿瘤密切相关。近年来在眼附属器黏膜相关淋巴组织(MALT)淋巴瘤中发现衣原体、丙肝病毒、幽门螺杆菌(HP)等病原菌,研究发现这些病原菌与眼附属器MALT淋巴瘤的发生发展及治疗等密切相关。而抗感染治疗相对安全有效,可以取代传统的外科手术、放疗、化疗等。胃MALT淋巴瘤与单一的HP感染密切相关,而眼附属器MALT淋巴瘤的感染性因素较多,且病例数较少,所以病原菌的种类及其与眼附属器MALT淋巴瘤的关系尚有待进一步研究。Infectious factors contribute to human cancers. In past few years, chlamydia, hepatitis C virus （HCV）and helicobacter pylori （HP）had been found in the mucosa-associated lymphoid tissue （MALT）lymphomas of ocular adnexa. The infectious factors had been considered to be associated with the oncogenesis, management and treatment of tumor. Antibiotic therapy against infectious factors may herald a future with a curtailed role for traditional therapies of surgery, radiation, and chemotherapy. Unlike MALT lymphoma of gastric related to a single infectious factor, multiple organisms may play a role in the etiology in MALT lymphoma of ocular adnexa. MALT lymphoma of ocular adnexa is seldom in clinic. The characteristics of MALT lymphoma of ocular adnexa,the relationship of MALT lymphoma of ocular adnexa and causal agents are reviewed.

关 键 词：黏膜相关淋巴瘤 眼附属器 衣原体 丙肝病毒 幽门螺旋杆菌 

分 类 号：R739.7[医药卫生—肿瘤]