数字化体层融合在肺结节探查中的初步应用  

Initial application of digital tomosynthesis for detection of pulmonary nodules

作　　者：孙志远[1] 苏宏[1] 赵艳娥[1] 鞠兵[1] 常双会[1] 胡秋菊[1] 卢光明[1] 

机构地区：[1]南京军区南京总医院医学影像科,210002

出　　处：《中华放射学杂志》2010年第1期33-36,共4页Chinese Journal of Radiology

摘　　要：目的探讨数字化体层融合在肺结节探查中的应用价值。方法30例疑有肺内结节的患者，均先后行胸部X线平片、体层融合和CT检查。将上述影像资料传至后处理工作站，由2名具有3年以上胸部影像诊断经验的医师分别进行双盲法阅片，观察每例患者肺部结节的数量，每个肺结节的部位、大小。然后，2名阅片者再共同阅片，使单独阅片不一致的结果得到统一。以CT结果作为标准，分别计算胸部X线平片和体层融合探查肺结节的敏感性。采用配对四格表资料的）（2检验比较两者的差异性。结果30例患者，胸部X线平片检查9例阴性，21例阳性，共发现肺结节40个。体层融合检查4例阴性，26例阳性，共发现肺结节89个。CT检查3例阴性，27例阳性，共发现肺结节102个。以CT作为标准对照，胸部X线平片探查肺结节的敏感性为27．4％（28／102），体层融合的敏感性为87．2％（89／102），差异有统计学意义（X2=4．35，P〈0．05）。结论数字化体层融合可显著提高肺结节探查的敏感性，可以作为胸部x线平片良好和必要的补充。Objective To discuss the value of digital tomosynthesis for detection of pulmonary nodules. Methods Thirty patients suspected of having pulmonary nodules underwent chest radiography, digital tomosynthesis and CT examination. Above image data were transferred to postprocessing work station and were reviewed by 2 radiologists with 3 years of chest-radiology diagnosis experience in a double-blind method. The number, location and size of nodules were recorded. Then, 2 radiologists reviewed the all images once more, and discuss in consensus. The sensitivities of chest radiography and digital tomosynthesis for detection of pulmonary nodules were respectively calculated according to the CT results. Chi-square test was used for radiography, digital tomosynthesis and CT examination. Results Of 30 patients, 21 were detected having pulmonary nodules by X-ray radiography and 9 were negative, the total number of 40 nodules was detected, while 89 nodules in 26 patients were detected by digital tomosynthesis, and only 4 patients were negative. CT demonstrated 102 nodules in 27 patients, and 3 patients were negative. Taking CT as ＂gold standard＂, the sensitivities of X-ray radiography and digital tomosynthesis were 27.4% （28/102） and 87.2% （ 89/102 ）, X^2 = 4.35, P 〈 0. 05, respectively. Conclusion Digital tomosynthesis has a high sensitivity for detection of pulmonary nodules compared with X-ray radiography, and could be an excellent and necessary supplementary technique of X-ray radiography.

关 键 词：硬币病变 肺 放射摄影术 体层摄影术 X线计算机 

分 类 号：R730.44[医药卫生—肿瘤]