动脉溶栓治疗急性基底动脉闭塞的研究进展  

Research Progress on Intra-arterial Thrombolysis for the Treatment of Acute Basilar Artery Occlusion

作　　者：张强[1,2] 兰晶[1,2] 池英[1,2] 张其梅[1,2] 李耀彩[1,2] 

机构地区：[1]三峡大学第一临床医学院 [2]宜昌市中心医院神经内科,宜昌443003

出　　处：《医学综述》2010年第1期77-78,共2页Medical Recapitulate

摘　　要：基底动脉闭塞是危及生命的严重脑血管事件,引起脑干梗死可迅速致死或致残,预后与颈内动脉系统闭塞性脑卒中相比较更差。传统的抗血小板,抗凝和静脉溶栓治疗效果并不理想,病死率高,幸存者多数致残甚至植物状态。目前认为在基底动脉系统闭塞后早期或超早期采用动脉溶栓等治疗方法,可使闭塞的基底动脉再通,降低患者的病死率,并使生存者的生活质量得到改善。Basilar artery occlusion is a severe life-threatening cerebrovascular event which can cause brainstem infarction and lead to quick death or disability, the prognosis of it is even poorer than the carotid artery occlusion. Conventional treatment such as antiplatelet and anticoagulation may not improve the clinical outcome, and cannot reduce the high fatality rate, most of the survivors are maimed or even turn into vegetative state. Currently, it is considered that local intra-arterial thrombolysis may recanalize the basilar artery ,thus reduce the mortality of acute basilar artery occlusion and improve the life quality of survivors.

关 键 词：基底动脉 闭塞 动脉 溶栓 

分 类 号：R741[医药卫生—神经病学与精神病学]