洛赛克胶囊联合阿莫西林胶囊、甲硝唑片治疗消化性溃疡并幽门螺杆菌感染的疗效  

Curative Effect of Peptic Ulcer and Helicobacter Pylori Infection in Treatment with Losec Capsule Combined with Amoxicillin Capsules and Metronidazole Tablets

作　　者：谢玮[1] 黄萍[1] 邹石[1] 

机构地区：[1]南昌大学医学院卫生科,南昌330006

出　　处：《实用临床医学（江西）》2009年第11期11-12,15,共3页Practical Clinical Medicine

摘　　要：目的观察洛赛克胶囊联合阿莫西林胶囊、甲硝唑片治疗消化性溃疡并幽门螺杆菌感染的临床疗效。方法48例消化性溃疡并幽门螺杆菌感染病人(其中胃溃疡15例,十二指肠溃疡33例),均给予洛赛克胶囊20 mg口服,2次/d;阿莫西林胶囊1.0 g口服,2次/d;甲硝唑片0.4 g口服,2次/d。疗程为7 d。48例病人疗程结束后4周复查胃镜,并检测幽门螺杆菌。结果48例病人中,愈合率为91.7%(44/48),有效率为96.4%(46/48),幽门螺杆菌根除率为87.2%(42/48)。结论洛赛克胶囊联合阿莫西林胶囊、甲硝唑片是治疗消化性溃疡并幽门螺杆菌感染的理想药物。Objective To observe the clinical curative effect of combined administration of Losec capsule, Amoxicillin capsules and Metronidazole tablets on peptic ulcer and Helicobacter pylori infection. Methods forty-eight peptic ulcer cases with Helicobacter pylori infection,including 15 cases of gastric ulcer and 33 of duodenal ulcer,were treated for 7 days with losec capsules （20 mg orally taken twice/d）, amoxicillin capsules （1.0 g orally taken twice/d）, and metronidazole tablets （0. 4 g orally taken twice/d）. At 4 weeks after the treatment, the patients underwent gastroscopy and detection of Helicobacter pylori. Results For the 48 patients, the healing rate was 91.7% （44/48） ,effectiveness rate was 96.4% （46/48）, Helicobacter pylori eradication rate was 87.2% （42/48）. Conclusion The combined administration of Losec capsule, Amoxicillin capsules and Metronidazole tablets may be an ideal therapy for peptic ulcer and Helicobacter pylori infection.

关 键 词：消化性溃疡 幽门螺杆菌 洛赛克胶囊 阿莫西林胶囊 甲硝唑片 治疗 

分 类 号：R573.1[医药卫生—消化系统]