金黄地鼠与大白鼠尿液成分的比较分析  

Comparison of Urine Components between Golden Hamsters and Rats

作　　者：李霞[1] 石俊[1] 姚林[2] 陈贵良[2] 陈则永[2] 于宗振[2] 周济桂[2] 

机构地区：[1]华北煤炭医学院附属医院检验科,唐山063000 [2]华北煤炭医学院医学实验动物中心,唐山063000

出　　处：《广东微量元素科学》1998年第9期27-29,共3页Trace Elements Science

摘　　要：通过比较分析，发现金黄地鼠尿液中蛋白、尿素氮、钾、钠、钙等明显高于大白鼠；金黄地鼠尿液粘稠，比重大，干枯后显白色，主要与尿液中高磷酸盐结晶、高蛋白及高尿素氮等有关。提出在蛋白从尿中大量损失后，仍未见金黄地鼠出现蛋白质缺乏性病理变化，其原因值得深究。金黄地鼠能否作为自发性高蛋白尿实验动物模型，有待进一步研究。The comparison of urine components was conducted between golden hamsters and rats. Theresults showed that the amount of protein (PRO), urine urea nitrogen (BUN), K+, Na+, Ca2+ from golden hamsters urine was significantly more than that of rats (P<0.01). High specific density and mucosity in urine of golden hamster were found. The white color of dried urine in golden hamster was related to high protein, urea nitrogen and phosphate of crystallization in urine. The pathologic change of protein deficiency was not found although there was a great amount of urine protein lost in golden hamster. A fur ther study is needed to explore if golden hamster can be taken as animal model of spontaneous hyperproteinuria.

关 键 词：金黄地鼠 大白鼠 尿液 化学成分 医用实验动物 

分 类 号：R－332[医药卫生]