中晚期宫颈癌术前经子宫动脉化栓塞对手术切除的影响  

Impact of Uterine Artery Chemoembolization before Surgical Operation in Patients with Advance Cervical Cancer

作　　者：禹海成[1] 吴泽涛[1] 何建军[1] 王玉琴[1] 袁新 

机构地区：[1]青海红十字医院介入室,810000 [2]青海省湟源县人民医院,812100

出　　处：《青海医药杂志》2009年第12期8-11,共4页Qinghai Medical Journal

摘　　要：目的:探讨经子宫动脉化疗栓塞对中晚期宫颈癌手术切除的影响。方法:对84例宫颈癌患者实施外科手术前子宫动脉化疗+栓塞术,抗癌药物为5-FU、顺铂、表阿霉素,灌注化疗后用表阿霉素10mg+碘化油10mL制成乳剂栓塞肿瘤供血动脉,再用明胶海绵条栓塞子宫动脉。结果:84例宫颈癌患者经(1～2)次术前动脉化疗栓塞术后顺利手术切除;术后标本病理切片中可见癌细胞坏死、退变及大量淋巴细胞浸润,其中8例病理学未见癌细胞。结论:宫颈癌术前动脉化疗栓塞术可使肿瘤缺血坏死、体积缩小、减少术中出血,还可改善肿瘤的临床分期为手术治疗创造机会,提高了患者的生存率,是一种安全有效的方法。objective：To understand the effects of uterine artey chemoembolization before operation on surgical treatment of cervical cancer.Methods：84 patients with cervical cancer,who would undergo surgical operation,received the uterine artery chemoembolization with epirubincin 10mg ＋ iodized oil before operation and after chemotherapy with epirubincin,5-FU and shunbo infusion and embolization of gelatin sponge.Results：The surgical resection of cervical cancer was performed successfilly in 84 patients,and the sample tissue from operation showed pathologically ischemic necrosis,degeneration and a large number of lymphocyte infiltration;and 8 samples of 84 patients did not find the cancer cell.Conclusions：The uterine artery chemoembolization before operation is a safe and effective way for treatment of cervical cancer,because it can induce to tumor necrosis and result in a successful chance of surgical operation.

关 键 词：宫颈癌 灌注化疗 栓塞 放射学 

分 类 号：R737.33[医药卫生—肿瘤]