单核细胞趋化蛋白-1与缺血性卒中  

Monocyte chemotactic protein-1 and ischemic stroke

作　　者：宋丽云[1] 王荔[1] 

机构地区：[1]山西医科大学第二医院神经内科,太原030001

出　　处：《国际脑血管病杂志》2009年第12期944-947,共4页International Journal of Cerebrovascular Diseases

基　　金：山西省高校科技研究开发项目（20091181）

摘　　要：炎症反应在缺血性卒中的发生和发展过程中起着重要作用。单核细胞趋化蛋白-1（monocyte chemotactic protein-1，MCP-1）是趋化因子CC类亚家族成员之一，可趋化和激活单核细胞、T细胞等多种细胞，促进细胞因子表达，参与缺血性脑损伤的发生。文章对MCP-1与缺血性卒中相关的研究进展做了综述。Inflammatory reaction plays an important role in the occurrence and development of ischemic stroke. Monocyte chemotactic protein-1 （MCP-1） is one of the subfamily members of the CC chemokine class. It can attract and activate a variety of cells, such as monocytes and T lymphocytes, promote the expression of cytokines, and participate in the occurrence of ischemie brain injury, This article reviews the progresses on the MCP-1 and ischemic stroke-related research.

关 键 词：趋化因子CCL2 动脉粥样硬化 卒中 炎症 

分 类 号：R743.3[医药卫生—神经病学与精神病学]