β-环糊精/聚乳酸接枝共聚物自组装胶束的制备与表征  

Preparation and Characterization of Micelles Self-Assembled by β-Cyclodextrin/Poly(Lactide) Graft Copolymer

作　　者：潘彤[1] 易兵[2] 谌其亭[1] 

机构地区：[1]长沙理工大学化学与生物工程学院,湖南长沙410004 [2]湖南工程学院化学化工学院,湖南湘潭411104

出　　处：《湘潭大学自然科学学报》2009年第4期37-40,共4页Natural Science Journal of Xiangtan University

基　　金：国家自然科学基金项目(20876016)

摘　　要：在水中制备了β-环糊精/聚乳酸接枝共聚物(β-CD-g-PLA)胶束,以芘为探针,采用稳态荧光法研究了胶束的形成及临界胶束浓度(CMC)),利用动态光散射(DLS)和透射电镜(TEM)研究了胶束的粒径分布和形态.结果表明,在一定条件下接枝共聚物在水中能够形成球形的稳定胶束,CMC值和胶束粒径随着共聚物中疏水性聚乳酸(PLA)链段含量的增加而减小.β--Cyclodextrin/poly （lactide） （β-CD-g-PLA） graft copolymer micelles were prepared in water. The fluorescence technique was used to determine the critical rnicelle concentrations （ CMC） of copol- ymer micelles. The diameter and distribution of micelles were characterized by dynamic light scattering （DLS） and its shape was observed by transmission electron microscopy （TEM） . The results showed that the round nano-micells were formed steadily by these copolymers in water. The CMC of copolymer solution and the size of micell were reduced with the increasing of the proportion of hydrophobic parts.

关 键 词：Β-环糊精 聚乳酸 接枝共聚物 临界胶束浓度 

分 类 号：O633[理学—高分子化学]