急性脑血管病患者合并医院感染危险因素的病例对照研究  

Case-control study of risk factors for nosocomial infections in patients with acute cerebrovascular diseases

作　　者：王建文[1] 孙娟[1] 

机构地区：[1]河北省廊坊市人民医院,河北廊坊065000

出　　处：《中国现代医学杂志》2009年第24期3807-3809,共3页China Journal of Modern Medicine

摘　　要：目的探讨急性脑血管病医院感染的影响因素,为有目的性地制定针对性预防措施提供客观依据。对策。方法回顾性分析我院480例急性脑血管病患者的临床资料,将医院感染作为观察组,无医院感染者作为对照组,对可能影响早产的因素资料进行单因素分析与Logistic回归分析。结果医院感染的发生率为9.25%(50/540);单因素分析医院感染的与性别、预防应用广谱抗生素无关(P>0.05),相关因素包括:年龄大、合并基础疾病、住院时间长、存在球麻痹、有意识障碍、伴呕吐、实施侵袭性操作、糖皮质激素、脱水剂及抑酸剂应用时间长P<0.05);经过Logistic回归分析,筛选出筛选出年龄大、合并基础疾病、有意识障碍、实施侵袭性操作4个因素与医院感染有关。结论医院感染是多因素综合作用的结果,通过对老年人重点保护、加强基础疾病的治疗、意识障碍者生命体征平稳后早期适量活动、尽可能减少侵袭性操作,有助于预防和控制医院感染的发生。【Objective】To probe into the risk factors for nosocomial infections in patients with acute cerebrovascular diseases so as to provide evidences for corresponding preventive measures.【Methods】The clinical data of 480 cases with acute cerebrovascular diseases in our hospital were retrospectively analyzed.The patients with nosocomial infections were included in the observation group,and those without in the control group.The possible influence factors were analyzed by single factor analysis and Logistic regression analysis.【Results】The rate of nosocomial infections was 9.25% （50/540）.Single factor analysis revealed that the infections were related to neither the patients＇age nor preventive usage of broad-spectrum antibiotics （P 〉0.05）;and the risk factors included old age,accompanied underlying diseases,long-term hospital stay,occurrence of bulbar paralysis,disturbance of consciousness,vomiting,application of invasive procedures,longtime usage of glucocorticoid,dehydrants and antacids （P 〈 0.05）.Logistic regression analysis screened out 4 factors related to nosocomial infections,i.e.old age,accompanied underlying diseases,disturbance of consciousness and application of invasive procedures.【Conclusion】Nosocomial infections result from multiple factors.It is helpful for prevention and control of nosocomial infections to take good care of the old patients,treat underlying diseases effectively,encourage the patients with disturbance of consciousness to have early and proper activities after stability of the vital signs and avoid invasive procedures.

关 键 词：急性脑血管病 医院感染 影响因素 病例对照研究 

分 类 号：R743[医药卫生—神经病学与精神病学]