肿瘤靶区呼吸运动实时反向跟踪系统在精确放疗中的应用研究  

Development of breath movement reverse tracking system for tumor precision radiotherapy

作　　者：伍锐[1] 陈超敏[1] 

机构地区：[1]南方医科大学生物医学工程学院,广东广州510515

出　　处：《南方医科大学学报》2010年第1期100-102,共3页Journal of Southern Medical University

基　　金：广东省科技计划项目(2007B01040056);广东省自然科学基金(2006024583)

摘　　要：目的在胸腹部肿瘤的精确放射治疗过程中,为了减少呼吸运动对肿瘤靶区精确定位的负面影响,使肿瘤靶区的呼吸运动范围尽可能缩小,以减少正常组织的受照范围,提高胸腹部肿瘤放射治疗定位精度。方法采用研制的逆向跟踪系统,通过图像引导的方式实时跟踪肿瘤靶区的呼吸运动,以此获取到靶区在某一特定时间段内的位移量,并尽可能快速地转化为相对于肿瘤靶区进行逆向运动的反馈信号,通过控制治疗床的运动,近似实现肿瘤位置对照射野中心的相对静止。结论能够有效地减少肿瘤靶区的呼吸移动对定位照射精度的影响,较好地满足了精确放射治疗的要求。与其他呼吸控制方法相对比,本方法具有避免延长照射时间、病人在治疗过程中可以自由呼吸、CT扫描时间短等优点。Objective To reduce the influence of breathing movement on the location precision of the tumor target in precise radiotherapy for thoraco-abdominal tumors. Methods An inverse tracking system was developed to track the path of the breathing movement of the tumor target via image guiding. With this system, the displacement of the target in a given time period was tracked and quickly transformed in signals that drove the tracking couch to move inversely relative to the tumor target. Conclusion This system can effectively reduce the influence of tumor target breath movement during radiotherapy. Compared with other breath movement control methods, this method avoids prolonged exposure time, allows the patient to breathe at ease and shortens the time of CT scanning.

关 键 词：放射治疗 逆向跟踪 呼吸运动 

分 类 号：R730.55[医药卫生—肿瘤]