180例健康人血浆神经肽Y相关因素的逐步回归分析  

The Stepwise Regression Analysis of the Related Factors with Plasma Neuropeptide Y in 180 Healthy People

作　　者：齐云萍[1] 邓洁[1] 马佳[1] 王南[1] 

机构地区：[1]云南省昆明市延安医院干部科干三病区,650051

出　　处：《医学研究杂志》2010年第1期98-100,共3页Journal of Medical Research

摘　　要：目的采用逐步回归分析180例健康人血浆神经肽Y因素进行探讨。方法通过放射免疫法进行测量血浆神经肽Y,同时通过心脏彩色超声测定右室舒张末期内径(RVDD)、室间隔舒张末期厚度(IVSd)、左室舒张末期内径(LVIDd)、左室后壁舒张末期厚度(LVPWd)、左室射血分数(EF)、左室每搏心排出量(SV)、心排出量(CO)、心指数(CI)和每搏指数(SI)。此外,还测定每个研究对象的身高、体重、血压、心率、皮下脂肪厚度等。结果不同性别和年龄的血浆神经肽Y无显著性差异(P≥0.05),健康人血浆神经肽Y的分布呈正态分布,95%正常值范围为70.27～190.61,99%正常值范围为51.23～209.65。结论血浆神经肽Y的主要相关因素是EF、体重、IVSD、舒张压、CO、SV和腹壁脂肪EF和体重与血浆神经肽Y呈负相关,其余5个因素与血浆神经肽Y呈正相关。ObjectiveTo explore the related factors with plasma neuropeptide Y in 180 normal healthy people by stepwise regression analysis. MethodsRight ventricular end-diastolic diameter（RVDD）, inter-ventricular septum end-diastolic thickness（IVST）, left ventricular end-diastolic diameter（LVDD）, left ventricular posterior wall end-diastolic thickness（LVPWT）, ejection fraction（EF）, strole volume（SV）, cardiac output（CO）, cadiac output index（CI）, stroke volume index（SI） and plasma neuropeptide Y were measured respectively by echocardiography and immunoradioassay in all subjects. In addition, we examined the height,weight,blood pressure,heart rate and subcutaneous fat thickness in every subjects. ResultsThe plasma neuropeptide Y wasn’t significant difference in different gender and age（P≥0.05）. The plasma neuropeptide Y of healthy population was normal distribution and the 95% of confidence interval 70.27 to 190.61,and 99% of confidence interval was 51.23 to 209.65. ConclusionThe EF,height,LVST,diastolic blood pressure,CO,SV and subcutaneous fat thickness were the major related-factors of neuropeptide Y in plasma. The EF and height were negatively correlated with plasma neuropeptide Y,and other five factors were postive correlated with it.

关 键 词：健康人 神经肽Y 正常值范围 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R174[医药卫生—临床医学]