胃癌螺旋CT强化与微血管密度表达关系的研究  

Study on relationship between spiral CT enhancement and MVD of gastric carcinoma

作　　者：吴国森[1] 唐咏梅[2] 王向明[1] 金其材[1] 

机构地区：[1]浙江省义乌市中心医院放射科 [2]浙江省义乌市中心医院病理科,浙江义乌322000

出　　处：《医学影像学杂志》2009年第12期1584-1587,共4页Journal of Medical Imaging

摘　　要：目的:探讨探讨术前胃癌螺旋CT强化与CD105标记的血管密度的关系,评价螺旋CT增强扫描对胃癌的临床意义。方法:对70例经病理证实为胃癌患者术前行CT增强扫描,术后用免疫组织化学染色方法检测CD105标记的血管密度,探讨其表达的关系及不同临床特征的意义。结果:螺旋CT分期与TNM临床分期完全符合率为84.28%,不同浸润深度、不同临床分期及有无淋巴结转移的比较中,螺旋CT扫描的强化值与血管密度的表达差异显著,且胃癌中螺旋CT扫描的强化值及血管密度的表达呈正相关。结论:胃癌患者术前行螺旋CT强化具有重要的意义,可能对早期判断患者预后及指导治疗有重要意义。Objective：To study the relationship between spiral CT enhancement and MVD, evaluate their clinical significance to preop- erative value. Methods：70 cases which were proved gastric carcinoma were studied by preoperative spiral CT enhancement. The expressions of CD105 protein were detected in gastric carcinoma tissues by immunohistochemistry. We observed their relationship and clinical characteristics. Results：The spiral CT stages were 84.28 % coincident whih TNM stage. The spiral CT enhancement and MVD were ob- viously correlated with penetrating depth, clinical stages and lymph node metastasis. There was positive correlation between spiral CT stage and MVD. Conclusion： The spiral spiral CT enhancement may be significant to evaluate the prognosis and treatment of gastric carcinoma.

关 键 词：胃癌 体层摄影术 X线计算机 CD105 血管生成 微血管密度 

分 类 号：R735[医药卫生—肿瘤] R814.42[医药卫生—临床医学]