多壁碳纳米管修饰电极检测盐酸氯丙嗪的研究  

Determination of chlorpromazine hydrochloride by cyclic voltammetry at a multiwall carbon nanotubes modified electrode

作　　者：李利军[1] 程龙军[2] 程昊[1] 蔡卓[2] 蓝苏梅[2] 吴晏玲[2] 

机构地区：[1]广西工学院生物与化学工程系,柳州545006 [2]广西大学化学化工学院,南宁530004

出　　处：《分析试验室》2010年第2期1-4,共4页Chinese Journal of Analysis Laboratory

基　　金：国家自然科学基金(20665001);广西科学基金(0640029)项目资助

摘　　要：制备了多壁碳纳米管修饰玻碳电极，采用循环伏安法（CT）研究了盐酸氯丙嗪在修饰电极上的电化学特性，发展了一种新的检测盐酸氯丙嗪的电化学分析方法。在最佳实验条件下，用循环伏安法检测盐酸氯丙嗪，其响应电流与盐酸氯丙嗪的浓度在8．0×10-5～1．0×10-3mol／L范围内有很好的线性关系，线性方程为Ip（A）=0．0106c（mol／L）-8×10-8（R2=0．999，n=6），检出限为6．2×10-6mol／L（S／N=3）。方法可用于盐酸氯丙嗪片的测定。A new method for the determination of Chlorpromazine Hydrochloride at the carbon nanotubes modified glassy carbon electrode was described. The electrochemical characteristics of chlorprornazine hydrochloride at this mod- ified electrode were studied by cyclic voltammetry in detail. Under the optimal conditions, the method showed good linearity for ehlorpromazine hydrochloride in the range of 8.0 × 10-5 - 1.0 × 10-3 mol/L in 0.05 mol/L H2SO4 with a detection limit of 6.2 × 10-6 mol/L （S/N = 3）. The proposed method showed high selectivity and sensitivity, and the disposal method of the sample was simple. The method was applied to the determination of chlorpromazine hydrochloride tablets.

关 键 词：循环伏安法 多壁碳纳米管 盐酸氯丙嗪 检测 

分 类 号：O657.1[理学—分析化学]