脑出血与高血压患者血浆内皮素含量对比分析  

A COMPARATIVE ANALYSIS OF THE ENDOTHELINBETWEEN CEREBRAL HEMORRHAGE AND HYPERTENSION

作　　者：刘罡[1] 齐晓飞[1] 刘建军[1] 闫广泽 毛永军[1] 

机构地区：[1]内蒙古医学院第一附属医院神经内科

出　　处：《内蒙古医学院学报》1998年第3期160-162,共3页Acta Academiae Medicinae Neimongol

摘　　要：目的：探讨脑出血与高血压患者血浆内皮素含量与病情的关系。方法：对４８例脑出血和３２例高血压患者的血浆内皮素浓度用放射免疫法进行测定及分析比较。结果：发现高血压型脑出血的急性期和Ⅲ期高血压患者血浆内皮素含量明显增高（Ｐ＜００１），且内皮素含量与病情呈正相关。结论：内皮素含量可间接反映病情及预后；但降压药物治疗后，内皮素含量变化不显著，说明降压药物不能抑制内皮素的释放。Objective: To investigate the relationship between the content of the endothelin in cerebral hemorrhage and hypertension and the patients condition.Methods:The level of plasma endothelin in 48 cases of cerebral hemorrhage and 32 cases of hypertension was assessed and compared.Results:It was showed that the content of the plasma endothelin was increased in the patients with hypertension cerebral hemorrhage and hypertension patients(P<001),and the endothelin was positively correlated with the patients condition.Conclusion:The content of endothelin can indirectly reflect of the condition and the prognosis of the patients.The content of the endothelin could not be changed evidently after the treatment with depressor to the hypertension patients.It is suggested that the depressor could not inhibit the release of the endothelin.

关 键 词：内皮素 脑出血 高血压 病理 预后 

分 类 号：R743.340.2[医药卫生—神经病学与精神病学] R544.102[医药卫生—临床医学]