Losec治疗老年人中重度返流性食管炎的疗效观察  

LOSEC IN TREATMENT OF MIDDLE AND SERIOUS REFLUX ESOPHAGITIS IN AGED

作　　者：龙治平[1] 王娟[1] 王育新[1] 

机构地区：[1]天津市第三医院消化内科

出　　处：《胃肠病学和肝病学杂志》1998年第3期266-267,265,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的为研究洛赛克（Ｌｏｓｅｃ）在Ｈ２受体拮抗剂治疗无效的老年人返流性食管炎治疗中的效果。方法经内镜检查确诊的返流性食管炎３７例（根据ＳａｖａｒｙＭｉｌｅｒ分级，２度２８例，３度９例）其中有食管裂孔疝８例，胃次全手术史７例，男２６例，女１１例，年龄５７７２岁，服用Ｌｏｓｅｃ２０ｍｇ，每日二次，结果正规治疗６周后，根据临床症状缓解消失情况和内镜复查的结果，总有率９４５９％（３５／３７）。结论治疗结果表明Ｌｏｓｅｃ治疗Ｈ２受体拮抗剂治疗无效的中重度返流性食管炎仍可取得很好效果，疗效可靠，副反应少而轻微，但用药剂量不能太小，因返流性食管炎复发率极高，尤其是老年人。Aims: To study the efficacy of Losec for therapy that treated uneffect with H 2 receptor antagonists of middle and serious reflux esophagitis in aged.Methods:Thirty seven patients(male 26,female 11,age 57 72Yr)diagnosed by endoscopy of reflux esophagitis.(Savary Miller,grade 2,28 cases;grade 3,9 cases).It was treated with Losec 20mg two time a day.Results: To be taken Losec after 6 weeks,the clinical and endoscopy total effective rate was 94.59%(35/37).Conclusion: The results show that the efficacy of Losec in treatment for that treated not effect with H 2 receptor antagonists of elderly reflux esophagitis was ideal,the adverse reactions of Losec was slight.But reflux esophagitis recurrent rates are high,maintaining treatment is required.

关 键 词：返流性食管炎 老年人 洛赛克 治疗 

分 类 号：R571.05[医药卫生—消化系统]