高频小探头内镜超声在胃癌术前T分期中的应用价值  

The utility of high frequency endoscopic ultrasound mini probe for preoperative T-staging of gastric cancer

作　　者：张召珍[1,2] 贺益萍[1,2] 沈俊[1,2] 许玲辉[3,2] 盛伟琪[4,2] 师英强[5,2] 

机构地区：[1]复旦大学附属肿瘤医院内镜科 [2]复旦大学上海医学院肿瘤学系,上海200032 [3]复旦大学附属肿瘤医院放射科 [4]复旦大学附属肿瘤医院病理科 [5]复旦大学附属肿瘤医院腹部外科

出　　处：《中国癌症杂志》2010年第1期44-49,共6页China Oncology

摘　　要：背景与目的:内镜超声是目前临床上广泛运用的胃癌术前分期的检查方法。内镜下黏膜切除术及黏膜剥离术在治疗早期胃癌中已广泛开展,因此提高胃癌术前分期的准确性,尤其是早期胃癌的诊断率。本文旨在探讨高频小探头内镜超声(high frequency endoscopic ultrasound mini probe,UMP)在胃癌术前T分期中的临床应用价值。方法:2008年10月-2009年4月,对63例胃癌患者术前分别行高频小探头内镜超声和多层螺旋CT(multislice spiral CT,MSCT)检查,并与手术后病理进行对照。结果:UMP与MSCT对T分期判断准确率分别为82.26%(51/62)和88.71%(55/62),差异无统计学意义(P>0.05)。UMP与MSCT对早期胃癌的诊断准确率分别为100.00%和88.89%;进展期胃癌的诊断准确率则是79.25%和88.68%。结论:UMP对早期胃癌诊断具有重要价值,因此对于内镜下查找浅表病灶应首选UMP。Background and purpose：Currently endoscopic ultrasonography is clinically accepted for preoperative staging of gastric cancers. Endoscopic mucosal resection （EMR） and endoscopic submucosal dissection （ESD） have been widely applied in the treatment of early gastric cancer. We need to improve the accuracy of pre-operative staging of gastric cancers, especially of early gastric cancers. This paper was to investigate the clinical significance of high frequency endoscopic ultrasound mini probe （UMP） in the preoperative T-staging of gastric cancer. Methods： Both UMP and MSCT were performed in 63 patients with pathologically proven gastric cancer from Oct. 2008 to Apr. 2009, and the results of UMP and MSCT were compared with surgical pathologic findings. Results：The accuracy of UMP and MSCT in T staging was 82.26% （51/62） and 88.71% （55/62） respectively, and there was no statistical difference （P〉0.05）. The accuracy of UMP and MSCT for early gastric cancer was 100.00% and 88.89% respectively. The accuracy of UMP and MSCT for advanced gastric cancer was 79.25% and 88.68% respectively. Conclusion： UMP appears to have a substantial diagnostic value for early stage gastric cancer. It is the approach of choice for superficial lesions.

关 键 词：胃癌 高频小探头内镜超声  多层螺旋计算机断层扫描  分期 

分 类 号：R735.2[医药卫生—肿瘤] R730.41[医药卫生—临床医学]