LEEP治疗310例宫颈病变的临床观察  

Efficacy of LEEP on the Treatment of Cervical Lesions:A Clinical Observation of 310 Women

作　　者：宋冬冬[1] 赵婧[1] 彭伟[1] 

机构地区：[1]广州新海医院,广州510300

出　　处：《热带医学杂志》2010年第1期56-57,75,共3页Journal of Tropical Medicine

摘　　要：目的探讨宫颈环形高频电波刀电切术(LEEP)治疗宫颈病变的临床应用价值。方法对液基细胞学(TCT)检查、阴道镜宫颈多点活检诊断为宫颈病变的310例患者进行LEEP术,其中慢性宫颈炎280例,宫颈湿疣5例,CINⅠ-Ⅱ级22例,CINⅢ级3例,切除组织全部送病检。同时观察手术时间、手术出血量及手术疗效。结果LEEP术后2个月慢性宫颈炎95%完全愈合,CIN术后2个月88%愈合,3个月后CIN患者100%愈合。手术前后病理诊断相吻合率为99%(307/310),仅3例有差异,其中1例术前CINⅡ,术后CINⅢ;1例术前CINⅢ,术后为原位癌;1例术前宫颈炎,术后为HPV感染。310例患者中,1例CINⅢLEEP术后病理报告为原位癌,LEEP切下之标本切缘未见病灶,患者本人要求子宫切除。结论LEEP术是目前治疗宫颈病变的最佳方法,且可提供完整的病检标本,对宫颈微浸润癌及原位癌的早期诊断价值高,是预防宫颈浸润癌的有效手段。Objective To evaluate the clinical value of loop electrosurgical excision procedure （LEEP） on treating cervical lesions. Methods 310 women with cervical lesions were selected for this study. Diagnostic methods included the liquid-based cytology and biopsy under the vaginoscope. 280 women were found to have chronic cervicitis. 5 women had cervical condyloma, 22 had cervical intraepithelial neoplasia-II （CIN-II）, and 3 had CIN-III. All the women were given LEEP treatment, and the tissues were sent to laboratory for pathological examination. Operation time, blood loss during the operation and the effectiveness of the operation were also recorded. Results Two months after the operation, 99% of the patients with chronic cervicitis were completely recovered. All patients with CIN were recovered 3 months after the operation. One of the CIN-III patients was found to have carcinoma in the cervix, and this patient decided to have total hysterectomy. Conclusion Currently, LEEP is the most appropriate method in treating cervical lesions. It can provide an intact specimen for pathological examination. It can not only be used for the diagnosis of carcinoma in situ of cervix, but also be used in the prevention of transformation of benign cervical lesions to invasive carcinoma.

关 键 词：宫颈环形电切术 宫颈上皮内瘤变 

分 类 号：R737.33[医药卫生—肿瘤]