大肠癌伴同时性肝转移126例临床分析  

Clinical analysis of 126 colorectal cancer cases with synchronous liver metastases

作　　者：王锡山[1] 陈洪生[1] 王贵玉[1] 邹德龄[1] 林树森[1] 尤琦[1] 

机构地区：[1]哈尔滨医科大学附属肿瘤医院结直肠外科,黑龙江150040

出　　处：《中华普外科手术学杂志（电子版）》2010年第1期28-30,共3页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

摘　　要：目的探讨大肠癌肝转移的临床特点与诊治效果。方法对126例大肠癌肝转移的临床资料进行回顾性总结分析。结果大肠癌同时性切除肝转移灶的手术切除率为17.5%(22/126),同时切除肝转移灶的病例1年生存率68.2%(15/22),3年生存率为40.9%(9/22),5年生存率为18.2%(4/22);而未切除肝转移灶的病例1年生存率为54.8%(57/104),3年生存率为16.3%(17/104),5年生存率为0%,两组生存率比较差异有显著性意义(P<0.05)。结论手术同时切除肝转移灶为大肠癌伴同时性肝转移的首选治疗方法。Objective To evaluate the clinical feature and the therapeutic effect of colorectal liver metastases. Methods The clinical data of 126 colorectal cancer patients with liver metastases were ana- lyzed retrospectively. Results Pata shoued that the rate of resection for both colorectal primary cancer and liver metastases was 17.5% （22/126）, and the 1-year survival rate was 68.2% （15/22）, the 3-year survival rate was 40.9% （9/22）, and the 5-year survival rate was18.2% （4/22）. In patients without hepatic resec- tion for mltastases, the 1-year survival rate was 54. 8% （57/104）, the 3-year survival rate was 16.3% （17/104） ,but no patients survived over 5 years. Comparison of the 3- and 5-year survival rates showed a significant difference. Conclusions The resection of synchronous liver metastasis is the first choice of therapy.

关 键 词：结直肠肿瘤 肝转移 结直肠外科手术 生存率 

分 类 号：R735.34[医药卫生—肿瘤] R735.2[医药卫生—临床医学]