银屑病患者外周血中循环内皮细胞的检测及其临床意义  

The Clinical Significance of Measuring CEC in Psoriatic Patients

作　　者：陈亚宝[1] 陈斯泰[1] 梁尚清[1] 叶军[1] 

机构地区：[1]江苏省泰州市人民医院,225300

出　　处：《中国微循环》2009年第6期557-559,共3页Journal of Chinese Microcirculation

摘　　要：目的探讨循环内皮细胞(CEC)在银屑病患者外周血中的变化及其临床意义。方法用流式细胞术检测47例正常对照和47例银屑病患者外周血中CEC的数量。结果①银屑病患者组CEC数量显著高于对照组(t=6.199,P<0.001);其中男性患者组显著高于男性对照组(t=4.570,P<0.001);女性患者组亦显著高于女性对照组(t=4.161,P<0.001)。②对照组,男性与女性比较无显著性差异(t=0.899,P>0.1);患者组,男性与女性比较亦无显著性差异(t=0.400,P>0.5)。结论CEC数量变化可能与银屑病的发病密切相关,银屑病患者CEC数量无性别差异。Objective To study the clinical significance of measuring circulating endothelial cells （CEC） in psoriatic patients. Methods CEC were measured in 47 normal control and 47 psoriatic patients by flowcytometry analysis. Results ①There were（male） and（female） endothelial cells in the control group and （male） and （female） in the psoriatic patients. The difference was statistically significant （ P 〈 0.001）. ②There were no significant differences between females and males in the control group （ t = 0. 899, P 〉 0. 1 ） or in the psoriatics （ t = 0. 400, P 〉 0. 5 ）. Conclusion The changes of CEC are closely related to the pathogenesis of psoriasis. No difference was found in endotbelemia in psoriatics according to the gender.

关 键 词：银屑病 循环内皮细胞 外周组 

分 类 号：R364.13[医药卫生—病理学]