平阳霉素注射治疗785例舌下腺囊肿疗效分析  

Treatment of sublingual cyst with intracystic injection of Pinyangmycin:clinical results in 785 consecutive cases

作　　者：赵苏峰[1] 寿卫东[1] 胡勤刚[1] 胡黎萍[1] 

机构地区：[1]南京大学医学院附属口腔医院口腔颌面外科,江苏南京210008

出　　处：《中国口腔颌面外科杂志》2010年第1期47-49,共3页China Journal of Oral and Maxillofacial Surgery

摘　　要：目的:评价平阳霉素注射治疗舌下腺囊肿的临床效果。方法:1997年1月—2009年1月,应用平阳霉素及地塞米松混合液注射治疗舌下腺囊肿785例。采用DXM 5mg/1mL配PYM 8mg加2%利多卡因3mL,按每1cm×1cm的囊肿内注入1mL混合药液(含PYM 2mg,DXM 1.25mg)酌情用药。7～10d注射1次,1～4次为1个疗程。囊肿完全消失者为治愈;囊肿基本消失,但患侧可触及变硬舌下腺者为基本治愈;囊肿缩小一半以上,不能完全消失需手术治疗者为好转。结果:785例患者中,男270例,女515例,年龄7个月～74岁,平均年龄为33.5岁。经6个月～48个月随访,治愈756例(96.31%),基本治愈26例(3.31%),好转3例(0.38%)。治愈和基本治愈率为99.62%,有效率为100%。31例(3.95%)注射区肿痛,舌缘麻木21例(2.68%),下颌下区肿痛11例(1.4%);未见高热、皮疹、休克等过敏反应。结论:平阳霉素联合地塞米松注射治疗舌下腺囊肿,安全有效,可作为某些病例的首选治疗方法。[Abstract] PURPOSE： The effect of combined Pinyangmycin（PYM） and dexamethasone injection to treat sublingual cyst was evaluated. METHODS： The medical records of 785 patients with sublingual cyst treated with Pinyangmycin injection between January 1997 and January 2009 was reviewed. Pinyangmycin and dexamethasone were combined and injected into the cyst of the sublingual gland. Aspirated mucus of ranula was replaced with an equal volume of PYM solution of 2mg/mU The size of ranula was compared before and after sclerotherapy. RESULTS： Seven hundred and eighty-five patients were followed up for 6 months to 48 months. 96.31% of the patients were cured, 3.31% had significant improvement, and 0.38% had improvement. CONCLUSION： Pinyangmycin injection is a safe and effective therapy for sublingual cyst, and can be used as a treatment of choice in some selected cases.

关 键 词：舌下腺囊肿 平阳霉素 地塞米松 

分 类 号：R782[医药卫生—口腔医学]